DMW – Klinischer Fortschritt, Table of Contents Dtsch Med Wochenschr 2014; 139(23): 1237-1239DOI: 10.1055/s-0034-1370032 Verdauungs- und Stoffwechselkrankheiten | Commentary Gastroenterologie, Infektiologie © Georg Thieme Verlag KG Stuttgart · New York Übertragung von Darmflora („Stuhltransplantation“): wann und für wen? Fecal microbiota transplantation: When and for whom? R. Schmelz 1 Medizinische Klinik und Poliklinik 1, Universitätsklinikum Carl Gustav Carus der TU Dresden , J. Hampe 1 Medizinische Klinik und Poliklinik 1, Universitätsklinikum Carl Gustav Carus der TU Dresden › Author Affiliations Recommend Article Abstract Buy Article Schlüsselwörter SchlüsselwörterStuhltransplantation - Clostridum difficile Keywords Keywordsfecal microbiota transplantation - Clostridium difficile Full Text References Literatur 1 Anderson JL, Edney RJ, Whelan K. Faecal microbiota transplantation in the management of inflammatory bowel disease. Aliment Pharmacol Ther 2012; 36: 503-516 2 Arumugam M, Raes J, Pelletier E et al. Enterotypes of the human gut microbiome. Nature 2011; 473: 174-180. Erratum: p. 666 3 Eiseman B, Silen W, Bascom GS et al. Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis. Surgery 1958; 44: 854-859 4 Gough E, Shaikh H, Manges AR. Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium difficile infection. Clin Infect Dis 2011; 53: 994-1002 5 Kassam Z, Lee CH, Yuan Y et al. Fecal microbiota transplantation for Clostridium difficile infection. Am J Gastroenterol 2013; 108: 500-508 6 Kump PK, Gröchenig HP, Lackner S et al. Alteration of intestinal dysbiosis by fecal microbiota transplantation does not induce remission in patients with chronic active ulcerative colitis. Inflamm Bowel Dis 2013; 19: 2155-2165 7 Ley RE, Turnbaugh PJ, Klein S et al. Microbial ecology: human gutmicrobes associated with obesity. Nature 2006; 444: 1022-1023 8 van Nood E, Vrieze A, Nieuwdorp M et al. Duodenal infusion of donor feces for recurrent Clostridium difficile. N Engl J Med 2013; 368: 407-415 9 Qin J, Li R, Raes J et al. MetaHIT Consortium: A human gut microbial gene catalogue established by metagenomic sequencing. Nature 2010; 464: 59-65 10 Ridaura VK, Faith JJ, Rey FE et al. Gut microbiota from twins discordant for obesity modulate metabolism in mice. Science 2013; 341: 1241214 11 Smits LP, Bouter KE, de Vos WM et al. Therapeutic potential of fecal microbiota transplantation. Gastroenterology 2013; 145: 946-953 12 Stepan C, Surawicz CM. Treatment strategies for C. difficile associated diarrhea. Acta Gastroenterol Latinoam 2007; 37: 183-191 13 Surawicz CM, Alexander J. Treatment of refractory and recurrent Clostridium difficile infection. Nat Rev Gastroenterol Hepatol 2011; 8: 330-339 14 Vardakas KZ, Polyzos KA, Patouni K et al. Treatment failure and recurrence of Clostridium difficile infection following treatment with vancomycin or metronidazole. Int J Antimicrob Agents 2012; 40: 1-8 15 Vrieze A, Van Nood E, Holleman F et al. Transfer of intestinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome. Gastroenterology 2012; 143: 913-916 16 Zhang F, Luo W, Shi Y et al. Should we standardize the 1,700-year-old fecal microbiota transplantation?. Am J Gastroenterol 2012; 107: 1755; author reply p. 1755-1776
