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Synlett 2014; 25(18): 2644-2648
DOI: 10.1055/s-0034-1379101
DOI: 10.1055/s-0034-1379101
letter
The Catalytic Synthesis of Carboniolamide: The Role of sp 3 Hybridized Oxygen
Weitere Informationen
Publikationsverlauf
Received: 19. Juli 2014
Accepted after revision: 18. August 2014
Publikationsdatum:
17. September 2014 (online)
Abstract
A catalytic synthesis of carboniolamide has been reported. The strategy was straightforward with aldehyde and amide as starting materials. The products can be isolated as precipitates from the reaction mixture. The factor that stabilizes the labile functionality of hemiaminal was elucidated as a sp 3 hybridized oxygen.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/products/ejournals/journal/ 10.1055/s-00000083.
- Supporting Information
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For some examples of the functional group assisted purification, see: