Synlett 2014; 25(19): 2791-2793
DOI: 10.1055/s-0034-1379305
letter
© Georg Thieme Verlag Stuttgart · New York

Friedel–Crafts Cyclodehydration Approach toward the Synthesis of Ellipti-cine and 9-Methoxyellipticine

Nagarajan Ramkumar
School of Chemistry, University of Hyderabad, Hyderabad 500 046, India   Fax: +91(40)23012460   eMail: rnsc@uohyd.ernet.in
,
Medishetty S. Raghavendra
School of Chemistry, University of Hyderabad, Hyderabad 500 046, India   Fax: +91(40)23012460   eMail: rnsc@uohyd.ernet.in
,
Rajagopal Nagarajan*
School of Chemistry, University of Hyderabad, Hyderabad 500 046, India   Fax: +91(40)23012460   eMail: rnsc@uohyd.ernet.in
› Institutsangaben
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Publikationsverlauf

Received: 21. August 2014

Accepted after revision: 21. September 2014

Publikationsdatum:
20. Oktober 2014 (online)


Abstract

An expedient synthesis of biologically important pyrido[4,3-b]carbazole alkaloids, ellipticine and 9-methoxyellipticine, is reported. Our synthetic approach applies a key H3PO4-mediated Friedel–Crafts cyclodehydration to construct the pyridine core.

Supporting Information