Synlett 2015; 26(12): 1683-1686
DOI: 10.1055/s-0034-1379929
letter
© Georg Thieme Verlag Stuttgart · New York

Gold- and Silver-Catalyzed Glycosylation with Pyranone Glycosyl Donors: An Efficient and Diastereoselective Synthesis of α-Anomers

Wenfeng Liu
a   School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong 510006, P. R. of China   Email: qianchen@gdut.edu.cn
,
Qian Chen*
a   School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong 510006, P. R. of China   Email: qianchen@gdut.edu.cn
,
Jiashen Liang
a   School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong 510006, P. R. of China   Email: qianchen@gdut.edu.cn
,
Zhiyun Du
a   School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong 510006, P. R. of China   Email: qianchen@gdut.edu.cn
,
Kun Zhang
a   School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong 510006, P. R. of China   Email: qianchen@gdut.edu.cn
,
Xi Zheng
a   School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, Guangdong 510006, P. R. of China   Email: qianchen@gdut.edu.cn
,
George A. O’Doherty
b   Department of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115, USA
› Author Affiliations
Further Information

Publication History

Received: 19 January 2015

Accepted after revision: 04 May 2015

Publication Date:
25 June 2015 (online)


Abstract

A mild, efficient and diastereoselective gold- and silver-catalyzed O-glycosylation with pyranone glycosyl donors is described. The reactions led to the formation of α-anomers in up to 91% yield with good diastereoselectivities.

Supporting Information