Synlett 2015; 26(07): 911-914
DOI: 10.1055/s-0034-1380141
letter
© Georg Thieme Verlag Stuttgart · New York

A Novel Nickel-Catalyzed Domino Method for the Direct Synthesis of Symmetrical Disulfides Using Potassium 5-Methyl-1,3,4-oxadiazole-2-thiolate as a Sulfurating Reagent

Mohammad Soleiman-Beigi*
Department of Chemistry, Basic of Sciences Faculty, Ilam University, PO Box 69315-516, Ilam, Iran   Email: SoleimanBeigi@yahoo.com   Email: m.soleimanbeigi@mail.ilam.ac.ir
,
Fariba Mohammadi
Department of Chemistry, Basic of Sciences Faculty, Ilam University, PO Box 69315-516, Ilam, Iran   Email: SoleimanBeigi@yahoo.com   Email: m.soleimanbeigi@mail.ilam.ac.ir
› Author Affiliations
Further Information

Publication History

Received: 07 December 2015

Accepted after revision: 14 January 2015

Publication Date:
18 February 2015 (online)


Abstract

A simple, one pot, efficient, and novel protocol has been developed for the direct synthesis of symmetrical organic disulfides using a domino reaction between an aryl/alkyl halide and potassium 5-methyl-1,3,4-oxadiazole-2-thiolate in the presence of NiCl2 as catalyst. A variety of symmetrical aryl/alkyl disulfides can be obtained in moderate to excellent yields (up to 95%).

Supporting Information