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Synlett 2015; 26(07): 937-941
DOI: 10.1055/s-0034-1380151
DOI: 10.1055/s-0034-1380151
letter
Bisnucleophilic Substitution as a Synthetic Tool for Ready Access to the Piperidine Alkaloids (+)-Connine, (+)-β-Conhydrine, (+)-8-Ethylnorlobelol, and (–)-Halosaline
Weitere Informationen
Publikationsverlauf
Received: 19. November 2014
Accepted after revision: 14. Januar 2015
Publikationsdatum:
19. Februar 2015 (online)
Abstract
Herein we report the stereoselective total synthesis of (+)-connine, (+)-β-conhydrine, (+)-8-ethylnorlobelol, and (–)-halosaline via bisnucleophilic substitution with benzylamine as the key step.
Key words
bisnucleophilic substitution - (+)-connine - (+)-β-conhydrine - (+)-8-ethylnorlobelol - (–)-halosaline - benzylamineSupporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0034-1380151.
- Supporting Information
-
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