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DOI: 10.1055/s-0034-1392274
Technical advances in endoscopic ultrasound-guided fiducial placement for the treatment of pancreatic cancer
Publication History
submitted: 20 December 2014
accepted after revision: 26 February 2015
Publication Date:
21 July 2015 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00025476/201504/lookinside/thumbnails/197_10-1055-s-0034-1392274-1.jpg)
Radiation therapy has an important role in the treatment of locally advanced or metastatic pancreatic cancer and can be used alone or in conjunction with surgery and/or systemic chemotherapy. Because of the challenge of delivering an accurate and optimal radiation dose, image-guided radiation therapy can be used to improve targeting. Fiducial markers can be placed in the tumor and used for localization in patients undergoing image-guided radiation therapy. The safety and feasibility of endoscopic ultrasound (EUS)-guided placement of fiducials has been assessed and reported for the management of pancreatic cancer. We herein review the technique, efficacy, and safety profile of EUS-guided fiducial placement. In addition, we highlight recent advances and technological upgrades in EUS-guided fiducial delivery systems for pancreatic cancer most relevant to practicing gastroenterologists and interventional endoscopists.
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