One-Pot Synthesis of O-Aryl Carbamates

Abstract

A simple, versatile, one-pot procedure for the synthesis of substituted O-aryl carbamates has been developed, and a protocol is henceforth described. N-Substituted carbamoyl chloride is formed in situ and subsequently reacted with a substituted phenol, avoiding the direct manipulation of sensitive reactants. This procedure offers an economical and efficient route to many compounds of interest.

Key words

O-aryl carbamates - phenyl carbamates - one-pot - versatile - safe - high yield

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