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Synlett 2016; 27(17): 2510-2514
DOI: 10.1055/s-0035-1562604
letter
© Georg Thieme Verlag Stuttgart · New York

Self-Assembled Nanoliposomes of Phosphatidylcholine: Bridging the Gap between Organic and Aqueous Media for a Green Synthesis of Hydroquinazolinones

Fatemeh Tamaddon*
Department of Chemistry, Yazd University, Yazd 89195-741, Iran   eMail: ftamaddon@yazduni.ac.ir
,
MohammadTaghi KazemiVarnamkhasti
Department of Chemistry, Yazd University, Yazd 89195-741, Iran   eMail: ftamaddon@yazduni.ac.ir
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Publikationsverlauf

Received: 15. Juni 2016

Accepted after revision: 06. Juli 2016

Publikationsdatum:
27. Juli 2016 (online)

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Abstract

Self-assembly of phosphatidylcholine in water creates liposomal nanoreactors for environmentally friendly synthesis of hydroquinazolinones by two- or three-component reactions, without the use of an extra catalyst or solvent. Recycling of the reaction medium and the absence of a need for other organic reagents are further advantages of this protocol.

Key words

liposomes - self-assembly - nanoreactors - phosphatidylcholine - hydroquinazolinones - green chemistry
 

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