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European J Pediatr Surg Rep. 2016; 04(01): 022-025
DOI: 10.1055/s-0036-1580704
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Extracalvarial Composite Infantile Myofibromatosis: Case Report and Literature Review

Alexander Ivanov
1   Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois, United States
,
Tibor Valyi-Nagy
2   Department of Pathology, University of Illinois at Chicago, Chicago, Illinois, United States
,
Dimitrios Nikas
1   Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois, United States
› Institutsangaben
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Publikationsverlauf

15. November 2015

14. Februar 2016

Publikationsdatum:
12. Juni 2016 (online)

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Abstract

Infantile soft tissue tumors of the head are very rare and the majority of them are myofibromas. The authors present the case of a 1-day-old boy with a scalp tumor with several distinct histopathological features including myofibroma, hemangiopericytoma, and fibrosarcoma consistent with the diagnosis of composite infantile myofibromatosis. Genetic testing was negative for trisomy 17, translocation (12; 15), FUS, and ETV6 translocations. Despite the ominous histopathological features, the clinical course was benign. The authors review here available literature concerning current concepts of making the diagnosis of composite infantile myofibromatosis and discuss treatment options.

Keywords

infantile myofibromatosis - composite infantile myofibromatosis - infantile fibrosarcoma
 

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