CC BY-ND-NC 4.0 · SynOpen 2017; 01(01): 0015-0023
DOI: 10.1055/s-0036-1588809
paper
Copyright with the author

A Mild and Efficient Method for the Syntheses and Regioselective Ring-Opening of Aziridines

Nirnita Chakraborty Ghosal
a   Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India
,
Sachinta Mahato
a   Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India
,
Rana Chatterjee
a   Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India
,
Sougata Santra
b   Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University, 19 Mira Str., 620002 Yekaterinburg, Russian Federation
,
Grigory V. Zyryanov
b   Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University, 19 Mira Str., 620002 Yekaterinburg, Russian Federation
c   Institute of Organic Synthesis, Ural Division of the Russian Academy of Sciences, 22 S. Kovalevskoy Str., 620219 Yekaterinburg, Russian Federation   Email: adinath.majee@visva-bharati.ac.in
,
Adinath Majee*
a   Department of Chemistry, Visva-Bharati (A Central University), Santiniketan 731235, India
› Author Affiliations
Further Information

Publication History

Received: 02 March 2017

Accepted after revision: 09 April 2017

Publication Date:
25 April 2017 (online)


Abstract

We have developed a new synthetic method for the synthesis of aziridines using Chloramine-T as an effective reagent in the presence of NH2OH·HCl and NaIO4. We found that the same combination of NH2OH·HCl and NaIO4 is also very effective for nucleophilic ring opening of aziridines.