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Synlett 2017; 28(16): 2143-2146
DOI: 10.1055/s-0036-1589066
DOI: 10.1055/s-0036-1589066
letter
Silver(I)-Catalyzed Deprenylation of Allylsulfonamide Derivatives
Further Information
Publication History
Received: 13 May 2017
Accepted after revision: 30 May 2017
Publication Date:
11 July 2017 (online)
![](https://www.thieme-connect.de/media/synlett/201716/lookinside/thumbnails/st-2017-u0355-l_10-1055_s-0036-1589066-1.jpg)
Abstract
The silver(I)-catalyzed deprenylation of sulfonamide bearing prenyl functional groups on the nitrogen atom has been developed. In this reaction, the prenyl moiety was selectively eliminated without allyl or benzyl cleavage on the nitrogen atom. In addition, geranyl was also applicable for this elimination reaction. Furthermore, sulfonamide possessing two prenyl groups underwent a double deprenylation to form the corresponding deprenylated sulfonamide. Thus, a novel reactivity between the silver cation and double bond was observed.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1589066.
- Supporting Information
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References and Notes
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