Photoorganocatalytic Atom Transfer Radical Addition of Bromoacetonitrile to Aliphatic Olefins

Errika Voutyritsa; Nikolaos F. Nikitas; Mary K. Apostolopoulou; Anna Dimitra D. Gerogiannopoulou; Christoforos G. Kokotos

doi:10.1055/s-0037-1610138

Synthesis, Table of Contents

Synthesis 2018; 50(17): 3395-3401
DOI: 10.1055/s-0037-1610138

special topic

Photoorganocatalytic Atom Transfer Radical Addition of Bromoacetonitrile to Aliphatic Olefins

Errika Voutyritsa

Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Athens 15771, Greece Email: ckokotos@chem.uoa.gr

,

Nikolaos F. Nikitas

Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Athens 15771, Greece Email: ckokotos@chem.uoa.gr

,

Mary K. Apostolopoulou

Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Athens 15771, Greece Email: ckokotos@chem.uoa.gr

,

Anna Dimitra D. Gerogiannopoulou

Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Athens 15771, Greece Email: ckokotos@chem.uoa.gr

,

Christoforos G. Kokotos*

Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Athens 15771, Greece Email: ckokotos@chem.uoa.gr

› Author Affiliations

Abstract

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Published as part of the Special Topic Photoredox Methods and their Strategic Applications in Synthesis

Abstract

A green and cheap protocol for the photocatalytic atom transfer radical addition (ATRA) of bromoacetonitrile to aliphatic alkenes is presented. The use of benzoin methyl ehter as the photocatalyst and irradiation using a household lightbulb leads to a highly useful synthetic method for the conversion of a wide range of substituted aliphatic olefins into the corresponding bromonitriles.

Key words

photoorganocatalysis - photochemistry - ATRA reaction - alkenes - bromoacetonitrile - nitriles

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References

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