Abstract
As pioneered by Corey and Chaykovsky, sulfoxonium ylides have had widespread application in organic synthesis for more than a half century. In most of the reactions, sulfoxonium ylides were used to react with electrophiles. Under suitable reaction conditions these ylides can generate metal carbenoids and react with nucleophiles. By combining the typical reactivity of sulfoxonium ylides with transition-metal catalysis, a growing number of investigations have expanded their application in organic synthesis. This review provides an update on the preparation of sulfoxonium ylides and their applications in carbenoid transfer reactions.
1 Introduction
2 Preparation of Sulfoxonium Ylides
3 Investigation for Carbenoid Formation from Sulfoxonium Ylide
4 X–H (X = N, O, S, C) Functionalization Reactions
5 Polymerizaton of Carbenoids Generated from Sulfoxonium Ylides
6 Conclusion and Perspective
Key words
sulfur ylides - metal carbenoids - transition metal catalysis - insertion reactions - C–H activation - coupling reaction - heterocycles
