Manganese(I)-Catalyzed Selective Functionalization of Alkynes

Zhongfei Yan; Chengjian Zhu; Jin Xie

doi:10.1055/s-0037-1610335

Synlett, Table of Contents

Synlett 2019; 30(02): 124-128
DOI: 10.1055/s-0037-1610335

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Manganese(I)-Catalyzed Selective Functionalization of Alkynes

Zhongfei Yan

,

Chengjian Zhu

,

Jin Xie*

State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, P. R. of China Email: xie@nju.edu.cn

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Abstract

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Abstract

Mn(I)-catalyzed selective functionalization of alkynes permits the convenient synthesis of substituted alkenes with high step and atom economies. Although the insertion of five-membered chelated manganacycle intermediates into alkynes has been widely reported, nonchelated Ar–Mn(I) species originating from commercially available arylboronic acids are unprecedented. Our new protocol achieved a challenging hydroarylation of unsymmetrical 1,3-diynes with arylboronic acids with complete regio-, stereo-, and chemoselectivity to give a wide array of trisubstituted conjugated (Z)-enynes in moderate to good yields.

Key words

arylboronic acids - alkynes - C–H activation - manganese catalysis - diynes - enynes

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References

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