Rh(III)-Catalyzed Olefination and Alkylation of Arenes with Maleimides: A Tunable Strategy for C(sp²)–H Functionalization

Abstract

We herein report a new nitrogen-directed Rh(III)-catalyzed C(sp²)–H bond functionalization of N-nitrosoanilines and azoxybenzenes with maleimides as a coupling partner, in which the olefination/alkylation process can be finely controlled at room temperature by variation of the reaction conditions. This method shows excellent functional group tolerance, and presents a mild access to the resulting olefination/alkylation products in moderate to good yields.

Key words

rhodium catalysis - nitrosoanilines - azoxybenzenes - olefination - alkylation

Publikationsverlauf

Eingereicht: 20. November 2020

Angenommen nach Revision: 27. Januar 2021

Artikel online veröffentlicht:
15. Februar 2021

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