Synthesis, Table of Contents Synthesis 2019; 51(02): 557-563DOI: 10.1055/s-0037-1610831 paper © Georg Thieme Verlag Stuttgart · New York Synthesis and Optical Resolution of 3,3,3′,3′-Tetramethyl-1,1′-spirobiindane-7,7′-diol Qiaoxia Zhou , Rihuang Pan , Huanyu Shan , Xufeng Lin * Laboratory of Asymmetric Catalysis and Synthesis, Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. of China Email: lxfok@zju.edu.cn › Author Affiliations Recommend Article Abstract Buy Article All articles of this category Abstract A novel chiral C2-symmetric spiro diol, 3,3,3′,3′-tetramethyl-1,1′-spirobiindane-7,7′-diol (TMSIOL), was conveniently prepared via practical seven-step route from Bisphenol A in 45.1% overall yield. l-Menthyl chloroformate is used as optical resolving agent for the separation of the two enantiomers of TMSIOL. Key words Key wordsasymmetric catalysis - chiral ligand - chiral diol - spirobiindane - resolution Full Text References References 1a Ojima I. 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