Thrombosis and Haemostasis, Table of Contents Thromb Haemost 2000; 83(03): 512-513DOI: 10.1055/s-0037-1613848 Letters to the Editor Schattauer GmbH An Effective Route for the Isolation of Human Genetic Loci Exemplified Using the BglI Restriction Fragment Length Polymorphism of the Factor VIII Gene Derrick J. Bowen Recommend Article Abstract Buy Article Full Text References Refrences 1 Saiki RK, Scharf S, Faloona F, Mullis KB, Horn GT, Erlich HA, Arnheim N. Enzymatic amplification of beta-globin genomic sequences and restriction site analysis for diagnosis of sickle cell anaemia. Science 1985; 230: 1350-4. 2 Gingrich JC, Boehrer DM, Garnes JA, Johnson W, Wong BS, Bergman A, Eveleth GG, Langlois RG, Carrano AV. Construction and characterisation of human chromosome-2 specific cosmid, fosmid and PAC clone libraries. Genomics 1996; 32: 65-74. 3 Bowen DJ, Hampton KK. Analysis of the BglI restriction fragment length polymorphism in the human factor VIII gene using “virtual PCR” - a novel approach employing the polymerase chain reaction in the absence of sequence information for the locus. Human Genetics 1996; 98: 219-22. 4 Antonarakis SE, Waber PG, Kittur SD, Patel AS, Kazazian Jr HH, Mellis MA, Counts RB, Stamatoyannopoulos G, Bowie EJ, Fas DN, Pittman DD, Wozney JM, Toole JJ. Haemophilia A: detection of molecular defects and of carriers by DNA analysis. New Engl J Med 1985; 313: 842-8. 5 Budowle B, Allen RC. Discontinuous polyacrylamide gel electrophoresis of DNA fragments. In: Protocols in human molecular genetics. Mathew CG. New Jersey: Humana Press; 1991: 128.
