Investigation of the Influence of Swallowing, Coughing and Vocalization on Heart Rate Variability with Respiratory-phase Domain Analysis

K. Kotani; M. Tachibana; K. Takamasu

doi:10.1055/s-0038-1625403

Methods of Information in Medicine, Table of Contents

Methods Inf Med 2007; 46(02): 179-185
DOI: 10.1055/s-0038-1625403

Original Article

Schattauer GmbH

Investigation of the Influence of Swallowing, Coughing and Vocalization on Heart Rate Variability with Respiratory-phase Domain Analysis

K. Kotani

¹Graduate School of Information Science and Technology, The University of Tokyo, Tokyo, Japan

,

M. Tachibana

²Graduate School of Engineering, The University of Tokyo, Tokyo, Japan

,

K. Takamasu

²Graduate School of Engineering, The University of Tokyo, Tokyo, Japan

› Author Affiliations

Abstract

Summary

Objectives : The objective of our study is to investigate extrinsic influences on heart rate variability using respiratory-phase domain analysis. Swallowing, coughing and vocalization (reading aloud and conversation) are adopted as extrinsic influences.

Methods : In this study, an instantaneous R-R interval (RRI) is sampled at each π/10 rad of the respiratory phase and the data is divided into three subsets: a) respiration with event, b) one respiration after the event, and c) normal respiration. Then the mean waveforms of respiratory sinus arrhythmia (RSA) are calculated and compared.

Results and Conclusions : It is found that swallowing induces tachycardia that recovers within one respiration. Coughing also induces tachycardia, but it does not recover within one respiration. Vocalization shortens the mean RRI, but the changing respiratory pattern due to vocalization has no statistically significant influence on the amplitude of RSA. Furthermore, it is found that the proposed method is effective for analyzing extrinsic influences on heart rate variability (HRV).

Keywords

Heart rate variability - respiratory phase - respiratory sinus arrhythmia

Full Text

References

References
1. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology.. Heart rate variability: standards of measurement, physiological interpretation and clinical use. Circulation 1996; 93: 1043-1065.
2. Katona PG., Jih F. Respiratory sinus arrhythmia: noninvasive measure of parasympathetic cardiac control. J Appl Physiol 1975; 39: 801-805.
3. Pomeranz B. Assesment of autonomic function in humans by heart rate spectral analysis. Am J Physiol 1985; 248: H151-153.
4. Kotani K, Hidaka I, Yamamoto Y, Ozono S. Analysis of respiratory sinus arrhythmia with respect to respiratory phase. Methods Inf Med 2000; 39: 153-156.
5. Kotani K, Tachibana M, Takamasu K. Repiratory phase domain analysis can estimate cardiac vagal activity accurately during a mental arithmetic task. Methods Inf Med.. In press
6. Han K, Nagel JH, Schneiderman N. A continuous representation of heart rate. Proc Ann Int Conf IEEE/EMBS 1992; 14: 785-786.
7. Rosenblum MG. Phase synchronization of chaotic oscillators. Phys Rev Lett 1996; 76: 1804-1807.
8. Ivanov PC. Multifractality in human heartbeat dynamics. Nature 1999; 399: 461-465.
9. Kiyono K, Struzik ZR, Aoyagi N, Sakata S, Hayano J, Yamamoto Y. Critical scale-invariance in healthy human heart rate. Phys Rev Lett. 2004 93: 178103-1-4
10. Aoyagi N, Ohashi K, Yamamoto Y. Frequency characteristics of long-term heart rate variability during constant routine protocol. Am J Phys 2003; 285: R171-176.