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Methods Inf Med 2004; 43(05): 479-482
DOI: 10.1055/s-0038-1633902
Original Article
Schattauer GmbH

Determination of the Population Size in an Epidemiological Study with Children

G. Ihorst
1   Institute of Medical Biometry and Medical Informatics, University Hospital of Freiburg, Freiburg, Germany
2   Center for Clinical Trials, University Hospital of Freiburg, Freiburg, Germany
,
J. Forster
3   St.-Josefs-Krankenhaus, Freiburg, Germany
,
G. Petersen
4   Wyeth Pharma GmbH, Münster, Germany
,
M. Schumacher
1   Institute of Medical Biometry and Medical Informatics, University Hospital of Freiburg, Freiburg, Germany
› Institutsangaben
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Publikationsdatum:
05. Februar 2018 (online)

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Summary

Objectives: To obtain a reliable estimate of the population size in an epidemiological study concerned with incidence estimation.

Methods: In the present case, the population of interest consists of all children attending a certain pediatric practice for any reason and is estimated making use of the number of regularly attended well baby visits. In some cases, exact figures from the practices are available as a reference. A prospective epidemiological study on the estimation of the incidence of lower respiratory tract infections (LRTI) in the German pediatric population (PRI.DE, Parainfluenza- und Respiratory-Syncytial-Virus-Infektionen in Deutschland) is used to demonstrate the procedure.

Results: In most cases, the fit can be regarded as good with deviations between 11% and 17%, whereas in a few cases it must be considered as poor (deviations of 60%).

Conclusions: The importance of using exact figures whenever obtainable and of appraising the results carefully is emphasized.

Keywords

Incidence estimation - population size - population at risk - children
 

  • References

  • 1 Schlaud M. (ed) Comparison and Harmonisation of Denominator Data for Primary Health Care Research in Countries of the European Community. Amsterdam: IOS Press; 1999
    Google Scholar
  • 2 Ehlken B, Laubereau B, Karmaus W, Petersen G, Rohwedder A, Forster J. and the RoMoD Study Group: Prospective population-based study on rotavirus disease in Germany. Acta Paediatr 2002; 91: 769-75.
    CrossrefPubMedGoogle Scholar
  • 3 Forster J, Ihorst G, Rieger CHL, Stephan V, Frank H, Gurth H, Berner R, Rohwedder A, Werchau H, Schumacher M, Tsai T, Petersen G. Prospective population-based study of viral lower respiratory tract infections in children under three years (the PRI. DE study). Accepted for publication in European Journal of Pediatrics.
    PubMedGoogle Scholar
  • 4 Glezen P, Denny FW. Epidemiology of acute lower respiratory disease in children. New Engl J Med 1973; 288: 498-505.
    CrossrefPubMedGoogle Scholar
  • 5 Pitkäranta A, Virolainen A, Jero J, Arruda E, Hayden FG. Detection of rhinovirus, respiratory syncytial virus, and coronavirus infections in acute otitis media by reverse transcriptase polymerase chain reaction. Pediatrics 1998; 102: 291-5.
    CrossrefPubMedGoogle Scholar
  • 6 Nationales Referenzzentrum für Influenza. Bericht zur Influenza-Situation 1997/98, 17.04.1998
    PubMed
  • 7 Kleinbaum DG, Kupper LL, Morgenstern H. Epidemiologic Research. Belmont, California: Wadsworth, Inc; 1983
    Google Scholar
  • 8 Statistisches Bundesamt (ed). Statistisches Jahrbuch. 2001. Stuttgart: Metzler-Poeschel; 2001
    Google Scholar