Imaging and the Human Brain Project: A Review

J. F. Brinkley; C. Rosse

doi:10.1055/s-0038-1634485

Methods of Information in Medicine, Table of Contents

Methods Inf Med 2002; 41(04): 245-260
DOI: 10.1055/s-0038-1634485

Original article

Schattauer GmbH

Imaging and the Human Brain Project: A Review^[*]

Authors

J. F. Brinkley

¹Structural Informatics Group, Department of Biological Structure, University of Washington, Seattle, USA
C. Rosse

¹Structural Informatics Group, Department of Biological Structure, University of Washington, Seattle, USA

Abstract

Summary

Objectives: Survey current work primarily funded by the US Human Brain Project (HBP) that involves substantial use of images. Organize this work around a framework based on the physical organization of the body.

Methods: Pointers to individual research efforts were obtained through the HBP home page as well as personal contacts from HBP annual meetings. References from these sources were followed to find closely related work. The individual research efforts were then studied and characterized.

Results: The subject of the review is the intersection of neuroinformatics (information about the brain), imaging informatics (information about images), and structural informatics (information about the physical structure of the body). Of the 30 funded projects currently listed on the HBP web site, at least 22 make heavy use of images. These projects are described in terms of broad categories of structural imaging, functional imaging, and image-based brain information systems.

Conclusions: Understanding the most complex entity known (the brain) gives rise to many interesting and difficult problems in informatics and computer science. Although much progress has been made by HBP and other neuroinformatics researchers, a great many problems remain that will require substantial informatics research efforts. Thus, the HPB can and should be seen as an excellent driving application area for biomedical informatics research.

Keywords

Neuroinformatics - imaging informatics - structural informatics - human brain project

Full Text

References

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Imaging and the Human Brain Project: A Review[*]

Authors

Imaging and the Human Brain Project: A Review^[*]