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DOI: 10.1055/s-0038-1635324
What Does an Observed Relative Risk Convey about Possible Misclassification?
Welche Folgerungen können aus einem beobachteten relativen Risiko über mögliche Mißklassifikationen gezogen werden?Publication History
Publication Date:
17 February 2018 (online)
![](https://www.thieme-connect.de/media/10.1055-s-00035037/198401/lookinside/thumbnails/10-1055-s-0038-1635324-1.jpg)
Summary
Misclassification of exposure in epidemiological studies has the effect of distorting the results in various directions. We give quantitative information about the possible order of magnitude of misclassification and of “true” effects given the observations of an epidemiological study. It will be demonstrated that misclassification can also distort trends in relative risks. Real examples from the epidemiological literature are used for illustration.
Mißklassifikationen der Exposition können in epidemiologischen Studien die Ergebnisse in verschiedener Hinsicht verzerren. Für gegebene beobachtete Daten einer epidemiologischen Studie werden quantitative Aussagen über die Größenordnung der Mißklassifikationen und der zugrundeliegenden »wahren« Effekte gemacht. Es wird gezeigt, daß durch Mißklassifikation ein Trend in den relativen Risiken verzerrt werden kann. Die Ergebnisse werden durch Beispiele aus der epidemiologischen Literatur illustriert.
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