Arrhythmia Curve Interpretation Using a Dynamic System Model of the Myocardial Pacemaker

Abstract:

A problem of identifying the phase response curve of the myocardial pacemaker was investigated using a simple dynamic system model of cardiac arrhythmia. A hybrid optimization method of a genetic algorithm and a local optimization technique was employed to obtain a solution of the model fitting. The method was applied to two categories of arrhythmias, ventricular parasystole and high-degree AV block. The present study offered a new insight into the mechanism of cardiac arrhythmias.

Keywords:

Arrhythmia - Phase Response Curve - Ventricular Parasystole - High-degree AV Block

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