The Absence of the Blood Clotting Regulator Thrombomodulin Causes Embryonic Lethality in Mice Before Development of a Functional Cardiovascular System

Robert D Rosenberg

doi:10.1055/s-0038-1642652

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1995; 74(01): 052-057
DOI: 10.1055/s-0038-1642652

Symposium

Vascular Wall Cells

Schattauer GmbH Stuttgart

The Absence of the Blood Clotting Regulator Thrombomodulin Causes Embryonic Lethality in Mice Before Development of a Functional Cardiovascular System

Authors

Robert D Rosenberg

Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA

Department of Medicine, Beth Israel Hospital, Harvard Medical School, Boston, MA, USA

Abstract

PDF Download

PDF (468 kb)

References

References
1 Esmon CT. Science. 1987; 235: 1348-1352
2 Conard J, Bauer KA, Gruber A, Griffin JH, Schwarz HP, Horellou M-H, Samama MM, Rosenberg RD. Blood. 1993; 82 (04) 1159-1164
3 Jackman RW, Beeler DL, VanDeWater L, Rosenberg RD. Proc Natl Acad SciUSA. 1986; 83: 8834-8838
4 Jackman RW, Beeler DL, Fritze L, Soff G, Rosenberg RD. Proc Natl Acad Sci USA. 1987; 84: 6425-6429
5 Wen D, Dittman WA, Ye RD, Deaven LL, Majems PW, Sadler JE. Biochem. 1987; 25: 4350-4357
6 Dittman WA, Kumada T, Sadler JE, Majerus PW. J Biol Chem. 1988; 263: 15815-15822
7 Soff G, Jackman RW, Rosenberg RD. Blood. 1991; 77 (03) 515-518
8 Imada S, Yamaguchi H, Nagumo N, Katayanagi S, Iwasaki H, Imada M. Dev Biol. 1990; 140: 113-122
9 Ford VA, Wilkinson JE, Kennel SJ. Roux’s Arch Dev Biol. 1993; 202: 364-370
10 Doetschman TC, Eistetter H, Katz M, Schmidt W, Kemler RJ. Embiyol Exp Moiph. 1985; 87: 27-45
11 George EL, Georges-Labouesse EN, Patel-King RS, Rayburn HB, Hynes RO. Develop. 1993; 119: 1079-1091
12 Bradley A. Production and analysis of chimeric mice. In Teratocarcinomas and Embryonic Stem Cells: A Practical Approach Robertson EJ. ed Oxford:IRL Press; 1987: 113-151
13 Chomczynski P, Sacchi NAnal. Biochem. 1987; 162: 156-159
14 Tsiang M, Lentz SR, Dittman WA, Wen D, Scarpati EM, Sadler JE. Biochem. 1990; 29: 10612-10612
15 Kennel SJ, Lankford T, Hughes B, Hotchkiss JA. Lab Invest. 1988; 59: 692-701
16 Salem HH, Maruyama I, Ishii H, Majerus PW. J Biol Chem. 1984; 259: 12246-12251
17 George EL, Hynes RO. Methods in Enzym in press. 1994
18 Baldwin HS, Lloyd TR, Solursh M. Circ Res. 1994; 74: 244-252
19 Fold VA, Kennel SJ. DNA Cell Biol. 1993; 12: 311-318
20 Hunter ES, Balkan T, Sadler TW. J Exp Zoology. 1988; 245: 264-269
21 Bertina RM, Koeleman BP C, Koster T, Rosendaal FR, Dirven RJ, de Ronde H, van der Velden PA, Reitsma PH. Nature. 1994; 369: 64-67
22 Miletich J, Sherman L, Broze G. The N E J of Med. 1987; 317 (16) 991-996
23 Bovill EG, Bauer KA, Dickerman JD, Callas P, West B. Blood. 1989; 73: 712-717
24 Johnson RS, van Lingen B, Papaioannou VE, Spiegelman BM. Genes & Dev. 1993; 7: 1309-1317
25 King BF. Am J Anat. 1972; 134: 365-376
26 Leung CC K. J Exp Zool. 1977; 200: 295-302
27 Soifer SJ, Peters KG, O’Keefe J, Coughlin SR. Am J Pathol. 1994; 144: 60-69
28 Inoue S, Leblond CP, Laurie GW. J Cell Biol. 1983; 97: 1524-1537
29 Carmeliet P, Schoonjans L, Keikens L, Ream B, Degen J, Bronson R, DeVos R, van den Oord JJ, Collen D, Mulligan RC. Nature. 1994; 368: 419-425