Tissue Factor: Then and Now^[*]

• 

Supported in part by Grant HL21019 from NHL

• References

• 1 Chargaff E, Moore DH, Bendich A. Ultracentrifugal isolation from lung tissue of a macromolecular protein component with thrombo-plastic properties. J Biol Chem 1942; 145: 593-603
• 2 Chargaff E, Bendich A, Cohen SS. The thromboplastin protein: structure, properties, disintegration. I Biol Chem 1944; 156: 161-178
• 3 Chargaff E. Studies on the mechanism of the thromboplastic effect. J Biol Chem 1948; 173: 253-262
• 4 Hvatum M, Prydz H. Studies on tissue thromboplastin. I. Solubilization with deoxycholate. Biochim Biophys Acta 1966; 130: 92-101
• 5 Hvatum M, Prydz H. Studies on tissue thromboplastin-its splitting into two separate parts. Thromb Diath Haemorrh 1969; 21: 217-222
• 6 Pitlick FA, Nemerson Y. Binding of the protein component of tissue factor to phospholipids. Biochem 1970; 9: 5105-5113
• 7 Contino PB. et al Anionic phospholipids and prothrombin transport are key regulators of thrombin generation in flowing plasma. XV^thCongress of the International Society on Thrombosis and Haemostasis, Jerusalem, Israel, 1995.
• 8 Bach R, Nemerson Y, Konigsberg W. Purification and characterization of bovine tissue factor. I Biol Chem 1981; 256: 8324-8331
• 9 Harlos K. et al Crystal structure of the extracellular region of human tissue factor. Nature 1994; 370: 662-666
• 10 Muller YA. et al Structure of the extracellular domain of human tissue factor: location of the factor Vila binding site. Biochem 1994; 33: 10864-10870
• 11 Bazan JF. Structural design and molecular evolution of a cytokine receptor superfamily. Proc Natl Acad Sci USA 1990; 87: 6934-6938
• 12 Ruf W, Edgington TS. Two sites in the tissue factor extracellular domain mediate the recognition of the ligand factor Vila. Proc Natl Acad Sci USA 1991; 88: 8430-8434
• 13 Kirchhofer et al.. Crystallization of the complex of factor Vila with cleaved tissue factor extra-cellular domain. XV^th Congress of the International Society on Thrombosis and Haemostasis, Jerusalem, Israel, 1995.
• 14 Banner D. et al The crystal structure of the complex of human factor Vila with human soluble tissue factor. XV^th Congress of the International Society on Thrombosis and Haemostasis, Jerusalem, Israel, 1995.
• 15 Taubman MB. et al Agonist-mediated tissue factor expression in cultured vascular smooth muscle cells. Role of Ca2 + mobilization and protein kinase C activation. J Clin Invest 1993; 91: 547-552
• 16 Conkling PR, Greenberg CS, Weinberg JB. Tumor necrosis factor induces tissue factor-like activity in human leukemia cell line U937 and peripheral blood monocytes. Blood 1988; 72: 128-133
• 17 Conway EM. et al Tumor necrosis factor enhances expression of tissue factor mRNA in endothelial cells. Thromb Res 1989; 53: 231-241
• 18 Moore KL. et al Endotoxin enhances tissue factor and suppresses thrombomodulin expression of human vascular endothelium in vitro. J Clin Invest 1987; 79: 124-130
• 19 Contrino J. et al In situ characterization of antigenic and functional tissue factor expression in human tumors utilizing monoclonal antibodies and recombinant factor Vila as probes. Amer J Pathol 1994; 145: 1315-1322
• 20 Silverberg SA, Nemerson Y, Zur M. Kinetics of the activation of bovine coagulation factor X by components of the extrinsic pathway. Kinetic behavior of two-chain factor VII in the presence and absence of tissue factor. J Biol Chem 1977; 252: 8481-8488
• 21 Drake TA. et al Functional tissue factor is entirely cell surface expressed on lipopolysaccharide-stimulated human blood monocytes and a constitutively tissue factor-producing neoplastic cell line. J Cell Biol 1989; 109: 389-395
• 22 Singanallore T. et al Localization of functionally active issue factor by in situ staining of human coronary arteries. XV^th Congress of the International Society on Thrombosis and Haemostasis, Jerusalem, Israel, 1995.
• 23 Nemerson Y, Gentry R. An ordered addition, essential activation model of the tissue factor pathway of coagulation: evidence for a conformational cage. Biochemistry 1986; 25: 4020-4033
• 24 Krishnaswamy et al. Role of the membrane surface in the activation of human coagulation factor X. J Biol Chem 1992; 267: 26110-26120
• 25 Andree et al. The activation of tissue factor-factor Vila incorporated into vesicles is controlled by short-range interactions and tissue factor clustering. XV^th Congress of the International Society on Thrombosis and Haemostasis, Jerusalem, Israel, 1995.
• 26 Repke D. et al Tissue factor (TF) in phosphatidyl choline (PC) has a higher K_cat than tissue factor in phosphatidyl serine (PS): implications for the role of acidic lipids in coagulation. XV^th Congress of the International Society on Thrombosis and Haemostasis, Jerusalem, Israel, 1995.
• 27 McCloskey M, Poo M-m. Protein diffusion in cell membranes: some biological implications. Inter Rev Cytol 1984; 87: 19-81
• 28 Pusey ML, Nelsestuen GL. The physical significance of in the prothrombinase reaction. Biochem Biophys Res Commun 1983; 114: 526-532
• 29 Gentry RD, Ye LQ, Nemerson Y. Computer simulations of the role of surfaces in the tissue factor pathway of coagulation. XV^thCongress of the International Society on Thrombosis and Haemostasis, Jerusalem, Israel, 1995.