Download PDF
Thromb Haemost 1995; 74(01): 278-281
DOI: 10.1055/s-0038-1642690
Symposium
Thrombosis Cancer
Schattauer GmbH Stuttgart

Cancer and Thrombosis: from Phlegmasia Alba Dolens to Transgenic Mice

Maria Benedetta Donati
Laboratory of Thrombosis Pharmacology, Istituto di Ricerche Farmacologiche “Mario Negri” Consorzio “Mario Negri Sud”, Santa Maria Imbaro, Italy
› Author Affiliations
Further Information

Publication History

Publication Date:
09 July 2018 (online)

Also available at
  PDF Download  Permissions and Reprints
 

  • References

  • 1 Trousseau A. Phlegmasia alba dolens. Lectures on clinical medicine, delivered at the Hôtel-Dieu, Paris. London: New Sydenham Society; 1872: 281-295
    Search in Google Scholar
  • 2 Sproul EE. Carcinoma and venous thrombosis: the frequency of association of carcinoma in the body or tail of the pancreas with multiple venous thrombosis. Am J Cancer 1938; 34: 566-585
    PubMedSearch in Google Scholar
  • 3 Donati MB, Poggi A. Malignancy and haemostasis. Br J Haematol 1980; 44: 173-182
    CrossrefPubMedSearch in Google Scholar
  • 4 Bini A, Mesa-Tejada R, Fenoglio JJ, Kudryk B, Kaplan KL. Immunohistochemical characterization of fibrin(ogen)-related antigens in human tissues using monoclonal antibodies. Lab Invest 1989; 60: 814-821
    PubMedSearch in Google Scholar
  • 5 Prandoni P, Lensing AW A, Biiller HR, Cogo A, Prins MH, Cattelan AM, Cuppini S, Noventa F, ten-Cate JW. Deep-vein thrombosis and the incidence of subsequent symptomatic cancer. N Engl J Med 1992; 327: 1128-1133
    CrossrefPubMedSearch in Google Scholar
  • 6 Monreal M, Lafoz E, Casals A, Inaraja L, Montserrat E, Ma Callejas J, Martorell A. Occult cancer in patients with deep venous thrombosis: a systematic approach. Cancer 1991; 67: 541-545
    CrossrefPubMedSearch in Google Scholar
  • 7 Rickies FR, Levine MN, and Edwards RI. Hemostatic alterations in cancer patients. Cancer Metastasis Reviews 1992; 11: 237-248
    CrossrefPubMedSearch in Google Scholar
  • 8 Falanga A, Ofosu F A, Cortellazzo S, Delaini F, Consonni R, Caccia R, Longatti S, Maran D, Rodeghiero F, Pogliani E, Marassi A, D’Angelo A, Barbui T. Preliminary study to identify cancer patients at high risk of venous thrombosis following major surgery. Briti sh Journal of Haematology 1993; 85: 745-750
    PubMedSearch in Google Scholar
  • 9 Falanga A, Barbui T, Rickies FR, Levine MN. Guidelines for clotting studies in cancer patients. Throm Haemostas 1993; 70: 540-542
    PubMedSearch in Google Scholar
  • 10 Levine MN, Gent M, Hirsh J, Arnold A, Goodyear MD, Hryniuk W, De Pauw S. The thrombogenic effect of anti-cancer drug therapy in women with stage II breast cancer. N Engl J Med 1988; 318: 404-407
    CrossrefPubMedSearch in Google Scholar
  • 11 Barbui T, Finazzi G, Donati MB, Falanga A. Antiblastic therapy and thrombosis. In: Thrombosis: an update. Scientific Press; Florence: 1992: 305-314
    Search in Google Scholar
  • 12 Levine M, Hirsh J, Gent M, Arnold A, Warr D, Falanga A, Samosh M, Bramwell V, Pritchard KI, Stewart D, Goodwin P. Double-blind randomised trial of very-low-dose warfarin for prevention of thromboembolism in stage IV breast cancer. Lancet 1994; 343: 886-889
    CrossrefPubMedSearch in Google Scholar
  • 13 Donati MB, Semeraro N. Cancer cell procoagulants and their pharmacological modulation. Haemostasis 1984; 14: 422-129
    PubMedSearch in Google Scholar
  • 14 Colucci M, Delaini F, De Beilis Vitti G, Locati D, Poggi A, Semeraro N, Donati MB. Warfarin inhibits both procoagulant activity and metastatic capacity of Lewis lung carcinoma cells. Role of vitamin K deficiency. Biochem Pharmacol 1983; 32: 1689-1691
    CrossrefPubMedSearch in Google Scholar
  • 15 Donati MB, Gambacorti Passerini C, Casali B, Falanga A, Vannotti P, Fossati G, Semeraro N, Gordon SG. Cancer procoagulant in human tumor cells: evidence from melanoma patients. Cancer Res 1986; 46: 6471-6474
    PubMedSearch in Google Scholar
  • 16 Falanga A, Bolognese D’Alessandro AP, Casali B, Roncaglioni MC, Donati MB. Several murine metastasizing tumors possess a cysteine proteinase with cancer procoagulant characteristics. Int J Cancer 1987; 39: 774-777
    CrossrefPubMedSearch in Google Scholar
  • 17 Bani MR, Falanga A, Alessio MG, Radice E, Consonni R, Giavazzi R, Donati MB. Blood coagulation changes in nude mice bearing human colon carcinomas. Int J Cancer 1992; 50: 75-79
    CrossrefPubMedSearch in Google Scholar
  • 18 Gordon SG, Hashiba V, Poole MA, Cross BA, Falanga A. A cysteine proteinase procoagulant from amnionchorion. Blood 1985; 66: 1261-1266
    PubMedSearch in Google Scholar
  • 19 Gordon SG, Cross BA. An enzyme-linked immunosorbent assay for cancer procoagulant and its potential as a new tumor marker. Cancer Res 1990; 50: 6229-6234
    PubMedSearch in Google Scholar
  • 20 Falanga A, Alessio MG, Donati MB, Barbui T. A new procoagulant in acute leukemia. Blood 1988; 870: 875
    PubMedSearch in Google Scholar
  • 21 Alessio MC, Falanga A, Consonni R, Bassan R, Minetti B, Donati MB, Barbui T. Cancer procoagulant in acute lymphoblastic leukemia. Eur. J.Haematol 1990; 45: 78-81
    PubMedSearch in Google Scholar
  • 22 Donati MB, Falanga A, Consonni R, Alessio MG, Bassan R, Buelli M, Catani L, Pogliani E, Gugliotta L, Masera G, Barbui T. Cancer procoagulant in acute non lymphoid leukemia: relationship of enzyme detection to disease activity. Thromb Haemostas 1990; 64: 11-16
    PubMedSearch in Google Scholar
  • 23 Falanga A, Consonni R, Marchetti M, Mielicki WP, Rambaldi A, Lanotte M, Gordon SG, Barbui T. Cancer procoagulant in the human promyelocytic cell line NB4 and its modulation by all-trans-retinoic acid. Leukemia 1994; 8: 156-159
    PubMedSearch in Google Scholar
  • 24 Falanga A, lacoviello L, Evangelista V, Belotti D, Consonni R, D’Orazio A, Robba L, Donati MB, Barbui T. Loss of blast cell procoagulant activity and improvement of hemostatic variables in patients with acute promyelocytic leukemia on All-trans-retinoic acid. Blood. 1995 in press
    PubMedSearch in Google Scholar
  • 25 Poggi A, Stella M, Donati MB. The importance of blood cell-vessel wall interactions in tumor metastasis. Bailliere Clinical Haematology 1993; 6: 731-752
    PubMedSearch in Google Scholar
  • 26 Zacharski LR, Donati MB, Rickies FR. Registry of clinical trials of antithrombotic drugs in cancer: second report. Thromb Haemostas 1993; 70: 357-360
    PubMedSearch in Google Scholar
  • 27 Poggi A, Bellelli E, Castelli MP, Marinacci R, Rella C, lacoviello L, Erickson LA, Donati MB, Bini A. Fibrinolysis and metastasis: the role of plasminogen activator inhibitor-1 (PAI-1) in a model of transgenic mice. Thromb Haemostas 1993; 69: 775
    PubMedSearch in Google Scholar
  • 28 Pintucci G, lacoviello L, Castelli MP, Amore C, Evangelista V, Cerletti C, Donati MB. Cathepsin G-induced release of PAI-1 in the culture medium of endothelial cells: a new thrombogenic role for polymorphonuclear leukocytes. J Lab Clin Med 1993; 122: 69-79
    PubMedSearch in Google Scholar
  • 29 Kolpakov V, D’Adamo MC, Salvatore L, Amore C, Mironov A, lacoviello L, Donati MB. Neutrophil derived cathepsin G induces potentially thrombogenic changes in human endothelial cells: a scanning electron mocroscopy study in static and dynamic conditions. Thromb Haemostas 1994; 72: 140-145
    PubMedSearch in Google Scholar
  • 30 lacoviello L, Kolpakov V, Salvatore L, Amore C, Pintucci G, de Gaetano G, Donati MB. Detachment of matrix-bound PAI-1 by neutrophil derived cathepsin G and subsequent cytoskeleton rearrangement in human endothelial cells. Atheroscler Thrombos. 1995 in press
    PubMedSearch in Google Scholar
  • 31 Giavazzi R, Garofalo A, Bani MR, Abbate M, Ghezzi P, Boraski D, Mantovani A, Dejana E. Interleukin-1 -induced augmentation of experimental metastases from human melanoma in nude mice. CancerRes 1990; 50: 4771-4775
    PubMedSearch in Google Scholar
  • 32 Bani MR, Garofalo A, Scanziani E, Giavazzi R. Effect of interleukin-16 on metastasis formation in different tumor systems. J Natl Cancer Inst 1991; 83: 119-123
    CrossrefPubMedSearch in Google Scholar