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Thromb Haemost 1995; 74(01): 360-363
DOI: 10.1055/s-0038-1642702
Symposium
Low Molecular Weight Heparin
Schattauer GmbH Stuttgart

Low Molecular Weight Heparins (LMWH) in the Treatment of Patients with Acute Venous Thromboembolism

Jack Hirsh
Hamilton Civic Hospitals Research Centre, Hamilton, Ontario, Canada
,
Sergio Siragusa
Hamilton Civic Hospitals Research Centre, Hamilton, Ontario, Canada
,
Benilda Cosmi
Hamilton Civic Hospitals Research Centre, Hamilton, Ontario, Canada
,
Jeffrey S Ginsberg
Hamilton Civic Hospitals Research Centre, Hamilton, Ontario, Canada
› Author Affiliations
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Publication History

Publication Date:
09 July 2018 (online)

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  • References

  • 1 Hirsh J, Levine M. Low molecular weight heparin. Blood 1992; 79: 1-17
    PubMedGoogle Scholar
  • 2 Lensing AW A, Prins MH, Davidson BL, Hirsh J. Treatment of deep-vein thrombosis with low molecular weight heparin. A meta-analysis. Arch Intern Med (in press)
    PubMedGoogle Scholar
  • 3 Leizorovicz A, Simonneau G, Decousus H, Boissel JP. Comparison of efficacy of low-molecular weight heparins and unfractionated heparin in initial treatment of deep vein thrombosis: a meta-analysis. Br Med J 1994; 309: 299-304
    CrossrefPubMedGoogle Scholar
  • 4 Green D, Hirsh J, Heit J, Prins M, Davidson B, Lensing AA W. Low molecular weight heparin: a critical analysis of clinical trials. Pharmacol Rev 1994; 46 (01) 89-109
    PubMedGoogle Scholar
  • 5 Hull RD, Raskob MB, Pineo GF, Green D, Trownbridge AA, Elliot G, Lemer RG, Hall J, Sparling T, Bretelli HR, Norton J, Carter CJ, George R, Merli G, Ward J, Mayo W, Rosenbloom D, Brant R. Subcutaneous low molecular weight heparin compared with continuous intravenous heparin in the treatment of proximal vein thrombosis. N Eng J Med 1992; 326 (15) 975-982
    CrossrefPubMedGoogle Scholar
  • 6 Prandoni P, Lensing AA W, Buller HR, Carta M, Cogo A, Vigo M, Casara D, Ruol A, ten Cate JW. Comparison of subcutaneous low molecular weight heparin with intravenous standard heparin in proximal deep vein thrombosis. Lancet 1992; 339: 441-445
    CrossrefPubMedGoogle Scholar
  • 7 Thery C, Simonneau G, Meyer G, Helenon O, Bridey F, Armagnac C, d’Zaemar P, Coquart JP. Randomized trial of subcutaneous LMWH CY216 (fraxiparine) compared with intravenous unfractionated heparin in the curative treatment of submassive pulmonary embolism. A dose ranging study Circulation 1992; 85 (04) 1380-1389
    CrossrefPubMedGoogle Scholar
  • 8 Duroux P, Beclere A. A Collaborative European Multicentre Study. A randomized trial of subcutaneous low molecular weight heparin (CY 216) compared with intravenous unfractionated heparin in the treatment of deep vein thrombosis Thromb Haemost 1991; 65 (03) 251-256
    Article in Thieme ConnectPubMedGoogle Scholar
  • 9 Lindmarker P, Holmstrom M, Granqvist S, Jonhs son H, Lockner D. Fragmin once daily subcutaneously in a fixed dose compared with continuous intravenous unfractionated heparin in the treatment of deep vein thrombosis. Thromb Haemost 1993; 69 (06) 648-648 (Abstract #381)
    Article in Thieme ConnectPubMedGoogle Scholar
  • 10 Lopaciuk S, Meissner J, Filipecki S, Zawilska K, Sowier J, Ciesielski L, Bielawiec M, Glowinski S, Czestochowska E. Subcutaneous low molecular weight heparin versus subcutaneous unfractionated heparin in the treatment of deep vein thrombosis: a Polish multicenter trial. Thromb Haemost 1992; 68 (01) 14-18
    Article in Thieme ConnectPubMedGoogle Scholar
  • 11 Simonneau G, Charbonnier B, Decousus H, Planchon B, Ninet J, Sie P, Silsiguen M, Combe S. Subcutaneous fixed dose of enoxaparine versus intravenous adjusted dose of unfractionated heparin in the treatment of deep vein thrombosis. Arch Intern Med 1993; 153: 1541-1546
    CrossrefPubMedGoogle Scholar
  • 12 Bratt G, Aberg W, Johansson M, Tomebohm E, Granqvist S, Lockner D. Two daily subcutaneous injections of fragmin as compared with intravenous standard heparin in the treatment of deep vein thrombosis. Thromb Haemosts 1990; 64 (04) 506-510
    PubMedGoogle Scholar
  • 13 Faivre R, Neuhart Y, Kieffer Y, Apfel F, Magnin D, Didier D, Toulemonde F, Bassand JP, Maurat JP. Un nouveau treatment des thromboses veineuses profondes: les fractions d’heparine de bas poids moleculaire. Presse Med 1988; 17 (05) 197-200
    PubMedGoogle Scholar
  • 14 Albada J, Nieuwenhuis HK, Sixma JJ. Treatment of acute thromboembolism with low molecular weight heparin (fragmin). Circulation 1989; 80 (04) 935-940
    CrossrefPubMedGoogle Scholar
  • 15 Bratt G, Tomebohm E, Granqvist S, Aberg W, Lockner D. A comparison between low molecular weight heparin (Kabi 2165) and standard heparin in the intravenous treatment of deep vein thrombosis. Thromb Haemost 1985; 54 (04) 813-817
    Article in Thieme ConnectPubMedGoogle Scholar
  • 16 Holm HA, Handeland GF, Albifgaard U, Amesen KE, Gottschalk P, Hoeg V, Ly B. Subcutaneous heparin treatment of deep vein thrombosis: a comparison of unfractionated and low molecular weight heparin. Haemosts 1986; 16 (02) 30-37
    PubMedGoogle Scholar
  • 17 Hardeland GF, Abilgaard U, Holm HA, Amesser KE. Dose adjusted heparin treatment of deep venous thrombosis; a comparison ofunfractionated and low molecular weight heparin. Eur J din Pharmacol 1990; 39 (02) 107-112
    PubMedGoogle Scholar