A Rapid Turbidimetric Determination of Fibrinogen Degradation Products (FDP)

H W Verbruggen; J M C Wessels

doi:10.1055/s-0038-1646119

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1978; 39(01): 012-021
DOI: 10.1055/s-0038-1646119

Original Article

Schattauer GmbH Stuttgart

A Rapid Turbidimetric Determination of Fibrinogen Degradation Products (FDP)

H W Verbruggen

The Division of Haematology, Department Internal Medicine, University of Nijmegen, The Netherlands

,

J M C Wessels

The Division of Haematology, Department Internal Medicine, University of Nijmegen, The Netherlands

› Author Affiliations

Abstract

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Summary

A rapid and simple turbidimetric determination of fibrinogen degradation products is described. This method is based on the increase of the turbidity due to the formation of precipitating antigen-antibody complexes after addition of rabbit antihuman fibrinogen antiserum to human serum. The increase in turbidity correlates very well with results obtained with the haemagglutination inhibition technique and has the advantage of a more objective quantitation. The reproducibility appears to be quite good. The turbidimetric method is independent of the colour of serum samples.

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References

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