A 3.5-Second Phenomenon in Haemostasis

D Thilo; E Böhm

doi:10.1055/s-0038-1649086

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1973; 30(02): 363-370
DOI: 10.1055/s-0038-1649086

Original Article

Schattauer GmbH

A 3.5-Second Phenomenon in Haemostasis

A Scanning Electron Microscopic Study

Authors

D Thilo

¹Blood Coagulation Laboratory (Head: Prof. Dr. F. Duckert) of the Department of Medicine (Director Prof. Dr. F. Koller) University of Basle, Switzerland

²Institute for Forensic Medicine (Director Prof. Dr. Spann), University of Munich, Germany
E Böhm

¹Blood Coagulation Laboratory (Head: Prof. Dr. F. Duckert) of the Department of Medicine (Director Prof. Dr. F. Koller) University of Basle, Switzerland

²Institute for Forensic Medicine (Director Prof. Dr. Spann), University of Munich, Germany

Abstract

Summary

Experiments with injury of the abdominal rat skin were carried out to examine the haemostatic system mechanism in vivo after zero to 30 seconds bleeding time. In the bleeding area only a few platelet aggregates could be found with no primary platelet thrombus. After 3.5 second bleeding time the first fibrin strands have been observed at the site of injury. The hypothesis is put forward that there is a very fast reacting haemostatic mechanism which results in the fibrin formation already at 3.5 seconds.

Full Text

References

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