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Am J Perinatol 2019; 36(13): 1362-1367
DOI: 10.1055/s-0038-1677471
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

The Use of Noninvasive Ventilation with High Frequency in Newborns—A Single-Center Experience

Beata Łoniewska
1   Department of Neonatal Diseases, Pomeranian Medical University, Szczecin, Zachodniopomorskie, Poland
,
Joanna Tousty
2   Department of Neonatal Diseases, Samodzielny Publiczny Szpital Kliniczny nr 2 Pomorskiego Uniwersytetu Medycznego, Szczecin, Zachodniopomorskie, Poland
,
Barbara Michalczyk
1   Department of Neonatal Diseases, Pomeranian Medical University, Szczecin, Zachodniopomorskie, Poland
,
Agnieszka Kordek
1   Department of Neonatal Diseases, Pomeranian Medical University, Szczecin, Zachodniopomorskie, Poland
,
Agata Jankowska
2   Department of Neonatal Diseases, Samodzielny Publiczny Szpital Kliniczny nr 2 Pomorskiego Uniwersytetu Medycznego, Szczecin, Zachodniopomorskie, Poland
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Publikationsverlauf

05. April 2018

16. November 2018

Publikationsdatum:
08. Januar 2019 (online)

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Abstract

Objective The aim of the study is to evaluate the efficacy of noninvasive high-frequency ventilation (nHFV) in respiratory-deficient infants.

Study Design Retrospective analysis of 32 cases of nHFV in 30 term (n = 4) and preterm (n = 26) newborns using a noninvasive ventilation (NIV) device. nHFV avoided intubation of children performed with NIV and reintubation after long-term mechanical ventilation (MV). Patients were divided into three groups: Group 1: NIV from birth (n = 18, mean birth weight [BW]: 1,987 g, gestational age [GA]: 33.1 weeks); Group 2: MV, also used temporarily, and NIV (n = 10, BW: 1,074 g, GA: 28.2 weeks); and Group 3: two cases with nHFV avoided reintubation after long-term MV (BW: 725 g, GA: 24.5 weeks).

Results From 32 episodes of nHFV application, positive effect was achieved 26 times (81%) (24 of 30 children). All newborns had a significant increase in pH (7.23–7.27) and reduction in partial pressure of CO2 (66.7–58.9 mm Hg, over 1–2 hours). Failures in application of nHFV reported only in Group 1 (6/18, 33%) (failures primarily due to increasing demand for oxygen). There were two reports of pneumothorax in preterm infants with congenital pneumonia. No other nHFV-related complications were noted.

Conclusion nHFV is a promising NIV mode which can be also used with NIV devices.

Keywords

noninvasive high-frequency ventilation - noninvasive ventilation - newborns - mechanical ventilation
 

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