Regioselective Diboron-Mediated Semireduction of Terminal Allenes

Ashley M. Gates; Webster L. Santos

doi:10.1055/s-0039-1690207

Synthesis, Table of Contents

Synthesis 2019; 51(24): 4619-4624
DOI: 10.1055/s-0039-1690207

paper

Regioselective Diboron-Mediated Semireduction of Terminal Allenes

Ashley M. Gates

,

Webster L. Santos ∗

Department of Chemistry, Virginia Tech, Blacksburg, VA 24061, USA Email: santosw@vt.edu

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Abstract

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Abstract

A method for the regioselective reduction of the terminal double bond of 1,1-disubstituted allenes has been developed. In the presence of a palladium catalyst, tetrahydroxydiboron and stoichiometric water, allene semireduction proceeds in high yield to afford Z-alkenes selectively.

Key words

diboron-mediated - allenes - hydrogenation - semireduction

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References

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