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Synthesis 2020; 52(07): 949-963
DOI: 10.1055/s-0039-1690813
DOI: 10.1055/s-0039-1690813
review
Iron Catalysis in Target Synthesis
We would like to thank the Engineering and Physical Sciences Research Council and CRITICAT Centre for Doctoral Training for financial support [PhD studentship to P.D.; Grant code EP/L0161419/1].Further Information
Publication History
Received: 09 December 2019
Accepted after revision: 19 January 2020
Publication Date:
05 February 2020 (online)
Abstract
The use of iron-catalysed organic transformations in the total syntheses of natural products has increased significantly. Iron-catalysed cross-coupling reactions are now widely applied in total syntheses and many other transformations, such as alkene functionalisation, oxidation, and cyclisation. The development of these processes, as well as many examples of their use in target synthesis, is presented here.
1 Introduction
2 Cross-Coupling Reactions
3 Functionalisation of Unactivated Alkenes
4 Carbocyclisation Reactions
5 Oxidations
6 Further Examples
7 Conclusions
-
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