Normal Variations and Pathologic Disorders of Chondrification and Ossification of the Foot and Related Diseases

Abstract

Formation of the skeletal elements of the foot involves different stages of development. Failure in segmentation of the cartilaginous plate is supposed to be the underlying mechanism leading to tarsal coalition. Variants or disorders in ossification might result in harmless osseous anomalies or symptomatic disease. When the ossification is almost completed, several secondary ossification centers start to ossify. They are usually incidental findings. In symptomatic patients they have to be differentiated from fractures or can be the source of complaints by themselves.

Keywords

foot - variants - osteochondrosis - ossicles - coalition

• References

• 1 Bernhardt DB. Prenatal and postnatal growth and development of the foot and ankle. Phys Ther 1988; 68 (12) 1831-1839
• 2 Harris BJ. Anomalous structures in the developing human foot. Abstract Anat Rec. 1955; 121: 399
• 3 Mellado JM, Ramos A, Salvado E, Camins A, Danus M, Sauri A. Accessory ossicles and sesamoid bones of the ankle and foot: imaging findings, clinical significance and differential diagnosis. Eur Radiol 2003; 13: L164-L177
• 4 Arnaiz J, Piedra T, de Lucas EM. , et al. Imaging findings of lower limb apophysitis. AJR Am J Roentgenol 2011; 196 (03) W316-W325
• 5 Tuthill HL, Finkelstein ER, Sanchez AM, Clifford PD, Subhawong TK, Jose J. Imaging of tarsal navicular disorders: a pictorial review. Foot Ankle Spec 2014; 7 (03) 211-225
• 6 Waugh W. The ossification and vascularisation of the tarsal navicular and their relation to Köhler's disease. J Bone Joint Surg Br 1958; 40-B [phone]
• 7 Danger F, Wasyliw C, Varich L. Osteochondroses. Semin Musculoskelet Radiol 2018; 22 (01) 118-124
• 8 Gillespie H. Osteochondroses and apophyseal injuries of the foot in the young athlete. Curr Sports Med Rep 2010; 9 (05) 265-268
• 9 Samim M, Moukaddam HA, Smitaman E. Imaging of Mueller-Weiss syndrome: a review of clinical presentations and imaging spectrum. AJR Am J Roentgenol 2016; 207 (02) W8-W18
• 10 Maceira E, Rochera R. Müller-Weiss disease: clinical and biomechanical features. Foot Ankle Clin 2004; 9 (01) 105-125
• 11 Harrison RB, Keats TE. Epiphyseal clefts. Skeletal Radiol 1980; 5 (01) 23-27
• 12 Torriani M, Thomas BJ, Bredella MA, Ouellette H. MRI of metatarsal head subchondral fractures in patients with forefoot pain. AJR Am J Roentgenol 2008; 190 (03) 570-575
• 13 Smillie IS. Treatment of Freiberg's infraction. Proc R Soc Med 1967; 60 (01) 29-31
• 14 Lyritis G. Developmental disorders of the proximal epiphysis of the hallux. Skeletal Radiol 1983; 10 (04) 250-254
• 15 Ceynowa M, Rocławski M, Pankowski R, Mazurek T. The prevalence and ossification pattern of the biphalangeal and triphalangeal lateral toes. Surg Radiol Anat 2018; 40 (09) 1039-1045
• 16 Mouchet A, Belot J. La tarsomegalie. J Radiol Electrol 1926; 10: 289-293
• 17 Glick R, Khaldi L, Ptaszynski K, Steiner GC. Dysplasia epiphysealis hemimelica (Trevor disease): a rare developmental disorder of bone mimicking osteochondroma of long bones. Hum Pathol 2007; 38 (08) 1265-1272
• 18 Rosero VM, Kiss S, Terebessy T, Köllö K, Szöke G. Dysplasia epiphysealis hemimelica (Trevor's disease): 7 of our own cases and a review of the literature. Acta Orthop 2007; 78 (06) 856-861
• 19 Tyler PA, Rajeswaran G, Saifuddin A. Imaging of dysplasia epiphysealis hemimelica (Trevor's disease). Clin Radiol 2013; 68 (04) 415-421
• 20 Bahk W-J, Lee H-Y, Kang Y-K, Park J-M, Chun K-A, Chung YG. Dysplasia epiphysealis hemimelica: radiographic and magnetic resonance imaging features and clinical outcome of complete and incomplete resection. Skeletal Radiol 2010; 39 (01) 85-90
• 21 Song MH, Cheon JE, Moon KC, Lee DY, Choi IH. Secondary synovial osteochondromatosis of the ankle in a child. Pediatr Radiol 2013; 43 (12) 1642-1646
• 22 Micheli LJ, Fehlandt Jr AF. Overuse injuries to tendons and apophyses in children and adolescents. Clin Sports Med 1992; 11 (04) 713-726
• 23 Scharfbillig RW, Jones S, Scutter SD. Sever's disease: what does the literature really tell us?. J Am Podiatr Med Assoc 2008; 98 (03) 212-223
• 24 Rachel JN, Williams JB, Sawyer JR, Warner WC, Kelly DM. Is radiographic evaluation necessary in children with a clinical diagnosis of calcaneal apophysitis (Sever disease)?. J Pediatr Orthop 2011; 31 (05) 548-550
• 25 Rossi I, Rosenberg Z, Zember J. Normal skeletal development and imaging pitfalls of the calcaneal apophysis: MRI features. Skeletal Radiol 2016; 45 (04) 483-493
• 26 Richli WR, Rosenthal DI. Avulsion fracture of the fifth metatarsal: experimental study of pathomechanics. AJR Am J Roentgenol 1984; 143 (04) 889-891
• 27 Karasick D. Fractures and dislocations of the foot. Semin Roentgenol 1994; 29 (02) 152-175
• 28 Forrester RA, Eyre-Brook AI, Mannan K. Iselin's disease: a systematic review. J Foot Ankle Surg 2017; 56 (05) 1065-1069
• 29 Gupta N, Sharma K, Bansal I, Kumar Y, Hayashi D. Kickboxing power hour: case report of fifth metatarsal apophysitis (Iselin disease) and its magnetic resonance imaging features. Transl Pediatr 2017; 6 (02) 98-101
• 30 Miller TT. Painful accessory bones of the foot. Semin Musculoskelet Radiol 2002; 6 (02) 153-161
• 31 Potter HG, Pavlov H, Abrahams TG. The hallux sesamoids revisited. Skeletal Radiol 1992; 21 (07) 437-444
• 32 Feldman F, Pochaczevsky R, Hecht H. The case of the wandering sesamoid and other sesamoid afflictions. Radiology 1970; 96 (02) 275-283
• 33 Karasick D, Schweitzer ME. Disorders of the hallux sesamoid complex: MR features. Skeletal Radiol 1998; 27 (08) 411-418
• 34 Sobel M, Pavlov H, Geppert MJ, Thompson FM, DiCarlo EF, Davis WH. Painful os peroneum syndrome: a spectrum of conditions responsible for plantar lateral foot pain. Foot Ankle Int 1994; 15 (03) 112-124
• 35 Bianchi S, Abdelwahab IF, Tegaldo G. Fracture and posterior dislocation of the os peroneum associated with rupture of the peroneus longus tendon. Can Assoc Radiol J 1991; 42 (05) 340-344
• 36 Lawson JP. International Skeletal Society Lecture in honor of Howard D. Dorfman. Clinically significant radiologic anatomic variants of the skeleton. AJR Am J Roentgenol 1994; 163 (02) 249-255
• 37 Lawson JP, Ogden JA, Sella E, Barwick KW. The painful accessory navicular. Skeletal Radiol 1984; 12 (04) 250-262
• 38 Miller TT, Staron RB, Feldman F, Parisien M, Glucksman WJ, Gandolfo LH. The symptomatic accessory tarsal navicular bone: assessment with MR imaging. Radiology 1995; 195 (03) 849-853
• 39 Günal I, Yörükoğlu K. Osteonecrosis of the accessory navicular bone. Arch Orthop Trauma Surg 2001; 121 (09) 546-547
• 40 McDougall A. The os trigonum. J Bone Joint Surg Br 1955; 37-B [phone]
• 41 Wiegerinck JI, Vroemen JC, van Dongen TH, Sierevelt IN, Maas M, van Dijk CN. The posterior impingement view: an alternative conventional projection to detect bony posterior ankle impingement. Arthroscopy 2014; 30 (10) 1311-1316
• 42 Giannini S, Buda R, Mosca M, Parma A, Di Caprio F. Posterior ankle impingement. Foot Ankle Int 2013; 34 (03) 459-465
• 43 Karasick D, Schweitzer ME. The os trigonum syndrome: imaging features. AJR Am J Roentgenol 1996; 166 (01) 125-129
• 44 Umans H. Ankle impingement syndromes. Semin Musculoskelet Radiol 2002; 6 (02) 133-139
• 45 Hayashi D, Roemer FW, D'Hooghe P, Guermazi A. Posterior ankle impingement in athletes: pathogenesis, imaging features and differential diagnoses. Eur J Radiol 2015; 84 (11) 2231-2241
• 46 Thiel E, Feibel J, Chorey N, Gorsline R. Bipartite talus: a case report. Foot Ankle Int 2010; 31 (06) 552-555
• 47 Case DT, Ossenberg NS, Burnett SE. Os intermetatarseum: a heritable accessory bone of the human foot. Am J Phys Anthropol 1998; 107 (02) 199-209
• 48 Nakasa T, Fukuhara K, Adachi N, Ochi M. Painful os intermetatarseum in athletes: report of four cases and review of the literature. Arch Orthop Trauma Surg 2007; 127 (04) 261-264
• 49 Reichmister JP. The painful os intermetatarseum: a brief review and case reports. Clin Orthop Relat Res 1980; 153 (153) 201-203
• 50 Hodge JC. Anterior process fracture or calcaneus secundarius: a case report. J Emerg Med 1999; 17 (02) 305-309
• 51 Ingalls J, Wissman R. The os supranaviculare and navicular stress fractures. Skeletal Radiol 2011; 40 (07) 937-941
• 52 Solomon LB, Rühli FJ, Taylor J, Ferris L, Pope R, Henneberg M. A dissection and computer tomograph study of tarsal coalitions in 100 cadaver feet. J Orthop Res 2003; 21 (02) 352-358
• 53 Newman JS, Newberg AH. Congenital tarsal coalition: multimodality evaluation with emphasis on CT and MR imaging. Radiographics 2000; 20 (02) 321-332 ; quiz 526–527, 532
• 54 Cowell HR, Elener V. Rigid painful flatfoot secondary to tarsal coalition. Clin Orthop Relat Res 1983; (177) 54-60
• 55 Pachuda NM, Lasday SD, Jay RM. Tarsal coalition: etiology, diagnosis, and treatment. J Foot Surg 1990; 29 (05) 474-488
• 56 Crim JR, Kjeldsberg KM. Radiographic diagnosis of tarsal coalition. AJR Am J Roentgenol 2004; 182 (02) 323-328
• 57 Lateur LM, Van Hoe LR, Van Ghillewe KV, Gryspeerdt SS, Baert AL, Dereymaeker GE. Subtalar coalition: diagnosis with the C sign on lateral radiographs of the ankle. Radiology 1994; 193 (03) 847-851
• 58 Conway JJ, Cowell HR. Tarsal coalition: clinical significance and roentgenographic demonstration. Radiology 1969; 92 (04) 799-811
• 59 Pistoia F, Ozonoff MB, Wintz P. Ball-and-socket ankle joint. Skeletal Radiol 1987; 16 (06) 447-451
• 60 Takakura Y, Tamai S, Masuhara K. Genesis of the ball-and-socket ankle. J Bone Joint Surg Br 1986; 68 (05) 834-837
• 61 Rozansky A, Varley E, Moor M, Wenger DR, Mubarak SJ. A radiologic classification of talocalcaneal coalitions based on 3D reconstruction. J Child Orthop 2010; 4 (02) 129-135
• 62 Linklater J, Hayter CL, Vu D, Tse K. Anatomy of the subtalar joint and imaging of talo-calcaneal coalition. Skeletal Radiol 2009; 38 (05) 437-449
• 63 Wechsler RJ, Schweitzer ME, Deely DM, Horn BD, Pizzutillo PD. Tarsal coalition: depiction and characterization with CT and MR imaging. Radiology 1994; 193 (02) 447-452