Subscribe to RSS

DOI: 10.1055/s-0040-1703721
RENAL CELL CARCINOMA WITH OSSEOUS METAPLASIA OCCURRING IN A CONTRACTED KIDNEY - A RARE CASE REPORT

Abstract
Osseous metaplasia is a rare histologic feature associated with renal cell carcinoma, occurring in a contracted kidney is still rarer. Metaplastic bone formation within the renal tumor gives an appearance similar to that of calcification. It is difficult to distinguish between bone formation and calcification on the basis of radiological imaging alone. Prognostic significance of metaplastic bone formation in renal cell carcinoma is not clear, however some report suggest good prognosis as a result of limitation of tumor spread by bone formation. This case report highlights the occurrence of renal cell carcinoma with osseous metaplasia in a contracted kidney.
Publication History
Article published online:
26 April 2020
© .
Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India
-
References
- 1 Singh V, Sinha RJ, Sankhwar SN, Dalela D. Heterotopic bone formation in renal cell carcinoma: A diagnostic challenge. Indian J Can 2008; 45:126-127.
- 2 Divya Kriplani, Priti P Trivedi, Manoj J Shah. Renal cell carcinoma with osseous metaplasia. Journal of case reports 2013;3:165-168.
- 3 Cribbs RK, Ishaq M, Arnold M, O'Brien J, Lamb J, Frankel WL. Renal Cell Carcinoma with massive osseous metaplasia and bone marrow elements. Ann Diagn Pathol. 1999; 3:294-299.
- 4 Wang L, Park P, Zhang H, La Marca F. Bone morphogenetic protein 2 inhibits tumor growth of human renal cell carcinomas and induces bone formation. Int J Cancer 2012; 131:1941-1950.
- 5 Hartman RJ, Helfand BT, Dalton DP. Clear cell renal cell carcinoma with osseous metaplasia: a case report. Can J Uro 2011; 18:5564-5567.
- 6 Bielsa. O, J. Loreta, O. Arango, S. Serrano, A. Gilbert-Mas. Bone metaplasia in a case of bilateral renal cell carcinoma. Urol Int 2001; 66:55–56.