Nickel-Catalyzed Reductive Allylation of Aldehydes with Allyl Acetates

Abstract

Carbonyl allylation reactions constitute an important step in the formation of carbon–carbon reactions, and involve various related reactions that chiefly use allylmetal reagents. This report presents a nickel-catalyzed carbonyl allylation reaction using allyl acetate, which produces homoallyl alcohols in moderate to good yields, as an efficient methodology under reductive coupling conditions.

Key words

reductive allylation - nickel complex - allyl acetate - carbonyl addition - transition-metal catalysis

Publication History

Received: 01 September 2020

Accepted after revision: 01 October 2020

Article published online:
02 December 2020

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