Syntheses and Applications of Singh’s Catalyst

Manisha Khandelwal; Sumit Kumar Ray; Rama Kanwar Khangarot

doi:10.1055/s-0040-1707235

Synthesis, Table of Contents

Synthesis 2020; 52(23): 3577-3582
DOI: 10.1055/s-0040-1707235

short review

Syntheses and Applications of Singh’s Catalyst

Manisha Khandelwal

^aDepartment of Chemistry, University College of Science, Mohanlal Sukhadia University, Udaipur, Rajasthan-313001, India Email: ramakanwar@mlsu.ac.in

,

Sumit Kumar Ray

^bDepartment of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, MP-462066, India

,

Rama Kanwar Khangarot∗

^aDepartment of Chemistry, University College of Science, Mohanlal Sukhadia University, Udaipur, Rajasthan-313001, India Email: ramakanwar@mlsu.ac.in

› Author Affiliations

Abstract

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Dedicated to Professor Vinod K. Singh on the occasion of his 60^th birthday.

Abstract

Singh’s catalyst has emerged as one of the most promising and valuable catalysts in the field of asymmetric synthesis. Since its discovery, it has proven to be one of the best organocatalysts for asymmetric direct aldol reactions, and is equally efficient in aqueous and organic media. In this Short Review, we summarize reactions utilizing Singh’s catalyst under various conditions.

1 Introduction

2 Synthesis of Singh’s Catalyst

3 Applications in Asymmetric Synthesis

4 Conclusion

Key words

Singh’s catalyst - asymmetric direct aldol reaction - organocatalysis - enantioselective - diastereoselective - chemoenzymatic synthesis

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References

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