Subscribe to RSS
DOI: 10.1055/s-0040-1708640
Antidepressant Drug Effect on Periodontal Status in Chronic Periodontitis Patients
Abstract
Patients with problems related to central nervous system dysfunctions are often treated with psychotropic drugs. These include antipsychotics, antidepressants, mood stabilizers, anticonvulsants, and drugs blocking specific receptors in the brain such as anticholinergics or beta-blockers. However, these medications have serious side effects affecting the oral health. The purpose of this study is to explore antidepressant drug effect in chronic periodontitis patients.
Aim: To explore the effect of antidepressant drug in chronic periodontitis patients.
Material and Methods: The study comprised of 100 subjects, 50 periodontally healthy subjects, 50 chronic periodontitis subjects.Clinical examination was done and the following parameters were assessed: Gingival index, Clinical Attachment Loss.
Keywords
Antidepressant drugs - chronic periodontitis patients - periodontal status - psychiatric - diseasesPublication History
Received: 20 November 2015
Accepted: 16 April 2016
Article published online:
22 April 2020
© .
Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India
-
References
- 1 Lamy, M. (1984). Drugs and oral health. Journal of the Maryland State Dental Association, Vol.27, No.3, (December 1984), pp.125-130, ISSN 0025-4355.
- 2 American Dental Association [ADA] - Division of Communications. (2005). for the dental patient. How medications can affect your oral health. Journal of the American Dental Association, Vol.136, No.6, (June 2005), pp.831, ISSN 0002-8177
- 3 Smith, R. &Burtner, A. (1994). Oral side-effects of the most frequently prescribed drugs. Special care in dentistry, Vol.14, No.3, (May-June 1994), pp.96-102, ISSN 0275-1879.
- 4 Locker D. Concepts of oral health, disease and the quality of life. In: Slade GD, editor. Measuring oral health and quality of life. Chapel Hill: University of North Carolina, Dental Ecology; 1997, pp. 11-23.
- 5 Sreebny, L. & Schwartz, S. (1997). A reference guide to drugs and dry mouth: 2nd edition. Gerodontology, Vol.14, No.1, (July 1997), pp.33- 47, ISSN 0734-0664
- 6 Bardow, A.; Nyvad, B. &Nauntofte, B. (2001). Relationships between medication intake, complaints of dry mouth, salivary flow rate and composition, and the rate of tooth demineralization in situ. Archives of oral biology, Vol. 46, No.5, (May 2001), pp.413-423, ISSN 0003-9969.
- 7 Brow, E. & Hong, S. (1999). Antidepressant-induced bruxism successfully treated with gabapentin. Journal of the American Dental Association, Vol.130, No.10, (October 1999), pp.1467-1469, ISSN 0002-8177.
- 8 Trivedy C, Warnakulasuriya S, Peters T J. Arecanuts chewing have deleterious effects. Br Med J 1999; 318:1287.
- 9 Von Knorring, A. & Wahlin, Y. (1986). Tricyclic antidepressants and dental caries in children. Neuropsychobiology, Vol.15, No.3-4, (1986), pp.143-145, ISSN 0302-282X.
- 10 Friedlander, A. & Mahler, M. (2001). Major depressive disorder: psychopathology, medical management and dental implications. Journal of the American Dental Association,Vol.132, No.5, (May 2001), pp.629-638, ISSN 0002-8177
- 11 Elter JR, White BA, Gaynes BN, Bader JD. Relationship of clinical depression to periodontal treatment outcome. J Periodontol 2002 Apr; 73(4):4419.
- 12 Friedlander AH, Mahler ME.Major depressive disorder. Psychopathology, medical management and dental implications. J Am Dent Assoc 2001 May; 132(5):629-38.
- 13 Douglas B. Berkey and Frank A. Scannapieco.Medical considerations relating to the oral health of older adults. Special Care in Dentistry, Volume 33, Issue 4, pages 164–176, July/August 2013.
- 14 Maes M1, Berk M, Goehler L, Song C, Anderson G, Galecki P, Leonard B. Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways. BMC Med. 2012 Jun 29; 10:66.
- 15 Sudhanshu Sanadhya, Pankaj Aapaliya, Sorabh Jain, Nidhi Sharma, Garima Choudhary, and Nirali Dobaria. Assessment and comparison of clinical dental status and its impact on oral health-related quality of life among rural and urban adults of Udaipur, India: A cross-sectional study. J Basic Clin Pharm. March 2015-May 2015; 6(2): 50–58.