Download PDF
CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2017; 07(02): 004-007
DOI: 10.1055/s-0040-1708703
Original Article

Ascorbic Acid Levels in Systemically Healthy Patients with and Without Periodontitis

Amitha Ramesh
1   Professor, Department of Periodontics, A B Shetty Memorial Institue of Dental Sciences, Mangalore
,
Agumbe Priyanka Prakash
2   Post Graduate, Department of Periodontics, A B Shetty Memorial Institue of Dental Sciences, Mangalore
,
Arya Ashok
3   Intern, Department of Periodontics, A B Shetty Memorial Institue of Dental Sciences, Mangalore
,
Biju Thomas
4   Head of the Department, Department of Periodontics, A B Shetty Memorial Institue of Dental Sciences, Mangalore
› Author Affiliations
› Further Information
Also available at
  PDF Download Permissions and Reprints

Abstract

Introduction : Periodontitis is a multifactorial disease initiated by plaque. This slowly progressing disease affects the supporting structures of the teeth leading to attachment and bone loss. Nutrition plays an important role in the inflammation and this could be related to effect of nutrition on periodontal disease prevalence. Vitamin C also known as ascorbic acid is abundantly found in fruits and vegetables play a role in the periodontal disease. It can scavenge free oxygen radicals and protect lipid from peroxidation and is a potent antioxidant.

Materials and methods : A total of 50 systemically healthy subjects were selected and divided into control group A (25 subjects without chronic periodontitis) and test group B (25 subjects with chronic periodontitis) and blood samples were collected to assess ascorbic acid levels. The data obtained were subjected to statistical analysis.

Results : showed statistical significance (p value 0.004) in the ascorbic acid levels between the two groups.

Conclusion : The plasma ascorbic acid level was significantly reduced in systemically healthy individuals with chronic periodontitis when compared to systemically healthy without periodontitis which could be attributed to the protective nature of this vitamin in chronic disease like periodontitis.

Keywords

Ascorbic acid - chronic periodontitis - Antioxidant


Publication History

Received: 30 January 2016

Accepted: 06 May 2017

Article published online:
22 April 2020

© .

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 

  • References

  • 1 Robert JG. Current view of risk factors for periodontal diseases. J Periodontaal October 1996; 67: 1041-9.
  • 2 Woolfe SN, Hume WR, Kenny EB. Ascorbic acid and periodontal disease: a review of the literature. J West Soc Periodontal Abstr 1980; 29:44-56.
  • 3 Padh H. Vitamin C: never insights into its biochemical functions.1991;49(3):65-70.
  • 4 Kuzmanova D, Jansen IDC, Schoenmaker T, Nazmi K, Teeuw WJ, Bizzarro S, Loos BG, Velden van der U. Vitamin C in plasma and leucocytes in relation to periodontitis. J Clin Periodontol 2012; 39: 905–912.
  • 5 Buzino R, Brodarec A, Jusic M,et al. Epidemiology of angular stomatitis and bleeding gums. Int J Vitam Nutr Res 1973; 43:401-15.
  • 6 Russell AL. International nutrition surveys: a summary of preliminary dental findings. J Dent Res 1963;42(1):233-244.
  • 7 Suomalainen K, Sorsa T, Lindy O, Saari H, Konttinen Y, Uitto VJ. Hypochlorous acid indused activation of human neutrophil and gingival crevicular fluid collagenase can be inhibited by ascorbate. Scand J Dent Res 1991;99:397-405.
  • 8 Clark DE, Navia JM, Manson-Hing LR, Duncan HE. Evaluation of of alveolar bone in relation to nutritional status during pregnancy. J Dent Res 1990;69:890-95.
  • 9 Chappel ILC , Brock GR, Milward MR, Ling N, Matthews JB. Compromised GCF total antioxidant capacity in Periodontitis : cause or effect? J clin. periodontal 2007; 34: 103-10.
  • 10 Vishakha G, Ranjan M, Kapoor A, Sachdeva S. Melatonin: Linking Periodontal Disease and Systemic Health. British Journal of Cosmetic Dentistry 2012;1(1):1-20
  • 11 Chen, K.H. and Chang, M.L. Effect of dietary vitamin E and vitamin C on respiration and swelling of guinea pig mitochondria. J. Nutr. 108 (1978) :1616-20.
  • 12 Panjamurthy K, Manoharan S, Ramachandran CR. Lipid peroxidation and antioxidant status in patients with periodontitis. Cellular and molecular biology letters 2005;10:255-64.
  • 13 Pussinen PJ, Laatikainen T, G Alfthan, Asikainen S, Jousilahti P.Periodontitis is associated with a low concentration of vitamin C in plasma. Clinical and diagnostic labouratory immunology sept 2003;10(5):897-02
  • 14 Ismail AI, Burt BA, Eklund SA. Relationship between ascorbic acid intake and periodontal disease in the United States. J. Am.Dent. Assoc.1983; 107:927–31.
  • 15 Russel AI.International nutrition surveys: a preliminary summary of dental findings. J.Dent.Res.1963; 42:223-25.
  • 16 Nishida M, Grossi SG, Dunford RG, Ho A W, Trevisan M, Genco RJ. Dietary Vitamin C and risk of periodontal disease. J Periodontol 2000; 71:1215-23.