Tuberkulose

Zusammenfassung

Die Tuberkulose gehört zu den bedeutendsten Ursachen für Morbidität und Mortalität weltweit. Die zunehmende Entwicklung multiresistenter Stämme von Mycobacterium tuberculosis, besonders in der WHO Region Europa, ist sehr besorgniserregend. In jüngster Zeit wurden bedeutende Fortschritte auf den Gebieten der Tuberkulose-Prävention, -Diagnostik und -Therapie, sowie im Management der multiresistenten Tuberkulose erzielt. Wissenschaftliche Höhepunkte der letzten Monate sind in dieser Kurzübersicht zusammengestellt.

Abstract

Tuberculosis ranges among the most important causes of morbidity and mortality worldwide. The emergence of drug-resistant strains of Mycobacterium tuberculosis, especially in the WHO Region Europe, is of serious concern. Recently, important advances have been achieved in the areas of tuberculosis prevention, diagnosis and treatment and in the management of patients with multidrug-resistant tuberculosis. Recent highlights are being presented in this mini-review.

Schlüsselwörter

IGRA - MDR-TB - Gesamt-Genomsequenzierung - persönliche Medizin - update

Keywords

IGRA - MDR-TB - personalized medicine - whole-genome sequencing

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