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CC BY-NC-ND 4.0 · Journal of Health and Allied Sciences NU 2022; 12(01): 47-52
DOI: 10.1055/s-0041-1732812
Original Article

Effect of Resistance Training and Diet Intake on Spleen Structure of Ovariectomized Wistar Rats

Erika Steffany dos Santos Santana
1   Department of Aging Sciences, São Judas Tadeu University, São Paulo, Brazil
,
Carolinne Alves de Oliveira
1   Department of Aging Sciences, São Judas Tadeu University, São Paulo, Brazil
,
Francisca Iranni Alves Lima
1   Department of Aging Sciences, São Judas Tadeu University, São Paulo, Brazil
,
Ricardo Aparecido Baptista Nucci
1   Department of Aging Sciences, São Judas Tadeu University, São Paulo, Brazil
2   Department of Pathology, University of São Paulo Medical School, São Paulo, Brazil
,
Fernando Luiz Affonso Fonseca
3   Laboratory of Clinical Analysis, ABC District Medical School, Santo André, Brazil
4   Department of Pharmaceutical Sciences, Federal University of São Paulo, São Paulo, Brazil
,
Laura Beatriz Mesiano Maifrino 
3   Laboratory of Clinical Analysis, ABC District Medical School, Santo André, Brazil
5   Dante Pazzanese Institute of Cardiology, São Paulo, Brazil
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Abstract

Introduction Exercise is a key factor in immunity which may be affected by a different diet intake. Thus, we aimed to analyze the effects of diet intake and resistance training on spleen structure of ovariectomized female animals.

Materials and Methods Female Wistar rats were divided into eight experimental groups: sedentary and nonovariectomized animals plus vegetable protein diet (CVS) or animal protein diet (CAS); trained and nonovariectomized rats plus vegetable protein diet (CVT) or animal protein diet (CT); sedentary and ovariectomized groups plus vegetable protein diet (VOS) or animal protein diet (AOS); and trained and ovariectomized animals plus vegetable protein diet (VOT) or animal protein diet (AOT).

Results Groups submitted to both animal protein diet and resistance training, mainly ovariectomized groups, presented a great variability of collagen fibers type III, white pulp, and follicle structure in relation to the other spleen constituents.

Conclusion Resistance training with a vegetable protein diet may play a key factor to maintain spleen’s immune responses across age. However, animal protein diet is suggested to decrease spleen’s immune activity.

Keywords

aging - diet - exercise


Publication History

Article published online:
05 August 2021

© 2021. Nitte (Deemed to be University). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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