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DOI: 10.1055/s-0041-1741088
Ultrasound of Median Nerve in the Diagnosis of Carpal Tunnel Syndrome—Correlation with Electrophysiological Studies
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Abstract
Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy caused by impairment of the median nerve due to compression as it passes through the carpal tunnel.
The current gold standard in diagnosing CTS and nerve damage is by electrophysiological nerve conduction study (NCS). However, 10 to 25% of NCS results are falsely negative. Moreover, NCS remains an expensive and time-consuming procedure for patients. Ultrasonography serves as a real-time, well-tolerated, portable, and noninvasive tool for assessing the carpal tunnel.
This study aims to assess the role of high-frequency ultrasound of the median nerve at the wrist in evaluating CTS and correlate with NCS to determine whether sonography can be used as an alternative to NCS in diagnosing and grading CTS.
Source(s) of Support in the Form of Grants, Equipment, Drugs, or All of These
Nil.
Publication History
Article published online:
06 April 2022
© 2022. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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References
- 1 Dell PC, Guzewicz RM. Atypical peripheral neuropathies. Hand Clin 1992; 8 (02) 275-283 [Internet]
- 2 Phalen GS. The carpal-tunnel syndrome. Seventeen years' experience in diagnosis and treatment of six hundred fifty-four hands. J Bone Joint Surg Am 1966; 48 (02) 211-228
- 3 Mallouhi A, Pülzl P, Trieb T, Piza H, Bodner G. Predictors of carpal tunnel syndrome: accuracy of gray-scale and color Doppler sonography. AJR Am J Roentgenol 2006; 186 (05) 1240-1245
- 4 Atroshi I, Gummesson C, Johnsson R, Ornstein E. Diagnostic properties of nerve conduction tests in population-based carpal tunnel syndrome. BMC Musculoskelet Disord 2003; 4: 9
- 5 Witt JC, Hentz JG, Stevens JC. Carpal tunnel syndrome with normal nerve conduction studies. Muscle Nerve 2004; 29 (04) 515-522
- 6 Martinoli C, Bianchi S, Gandolfo N, Valle M, Simonetti S, Derchi LE. US of nerve entrapments in osteofibrous tunnels of the upper and lower limbs. Radiographics 2000;20(Spec No):S199–S213, discussion S213–S217
- 7 Brown JM, Yablon CM, Morag Y, Brandon CJ, Jacobson JA. US of the Peripheral Nerves of the Upper Extremity: A Landmark Approach. Radiological Society of North America; 2016
- 8 Martinoli C, Bianchi S, Cohen M, Graif M. [Ultrasound of peripheral nerves]. J Radiol 2005; 86 (12 Pt 2): 1869-1878
- 9 Silvestri E, Martinoli C, Derchi LE, Bertolotto M, Chiaramondia M, Rosenberg I. Echotexture of peripheral nerves: correlation between US and histologic findings and criteria to differentiate tendons. Radiology 1995; 197 (01) 291-296
- 10 Michelsen H, Posner MA. Medical history of carpal tunnel syndrome. Hand Clin 2002; 18 (02) 257-268
- 11 Bongers FJM, Schellevis FG, van den Bosch WJHM, van der Zee J. Carpal tunnel syndrome in general practice (1987 and 2001): incidence and the role of occupational and non-occupational factors. Br J Gen Pract 2007; 57 (534) 36-39
- 12 Murthy J, Meena AK. Carpal tunnel syndrome: how common is the problem in South India. Neurol India 1995; 43 (01) 26-28
- 13 Chammas M, Boretto J, Burmann LM, Ramos RM, Dos Santos Neto FC, Silva JB. Carpal tunnel syndrome - part I (anatomy, physiology, etiology and diagnosis). Rev Bras Ortop 2014; 49 (05) 429-436
- 14 Lozano-Calderón S, Anthony S, Ring D. The quality and strength of evidence for etiology: example of carpal tunnel syndrome. J Hand Surg Am 2008; 33 (04) 525-538
- 15 Assmus H, Schwerdtfeger K, Wüstner-Hofmann M, Selbmann HK. Zur Entstehung und Implementierung der Leitlinie “Diagnostik und Therapie des Karpaltunnelsyndroms”. Handchir Mikrochir Plast Chir 2007; 39 (04) 289-292
- 16 Amirfeyz R, Gozzard C, Leslie IJ. Hand elevation test for assessment of carpal tunnel syndrome. J Hand Surg [Br] 2005; 30 (04) 361-364
- 17 MacDermid JC, Wessel J. Clinical diagnosis of carpal tunnel syndrome: a systematic review. J Hand Ther 2004; 17 (02) 309-319
- 18 Boyer K, Wies J, Turkelson CM. Effects of bias on the results of diagnostic studies of carpal tunnel syndrome. J Hand Surg Am 2009; 34 (06) 1006-1013
- 19 Simpson JA. Electrical signs in the diagnosis of carpal tunnel and related syndromes. J Neurol Neurosurg Psychiatry 1956; 19 (04) 275-280
- 20 Watson JC. The electrodiagnostic approach to carpal tunnel syndrome. Neurol Clin 2012; 30 (02) 457-478
- 21 American Association of Electrodiagnostic Medicine, American Academy of Neurology, and American Academy of Physical Medicine and Rehabilitation. Practice parameter for electrodiagnostic studies in carpal tunnel syndrome: summary statement. Muscle Nerve 2002; 25 (06) 918-922 [Internet]
- 22 Fowler JR, Maltenfort MG, Ilyas AM. Ultrasound as a first-line test in the diagnosis of carpal tunnel syndrome: a cost-effectiveness analysis. Clin Orthop Relat Res 2013; 471 (03) 932-937
- 23 Mesgarzadeh M, Schneck CD, Bonakdarpour A. Carpal tunnel: MR imaging. Part I. Normal anatomy. Radiology 1989; 171 (03) 743-748
- 24 Stuart RM, Koh ESC, Breidahl WH. Sonography of peripheral nerve pathology. AJR Am J Roentgenol 2004; 182 (01) 123-129 cited 2016Jun22 [Internet]