We report the case of a 55-year-old woman with a tumor in the greater curvature of
the upper gastric body. The tumor was incidentally found on an upper gastrointestinal
X-ray series performed during a routine medical examination. Whereas endoscopy revealed
a gastric submucosal tumor (SMT), endoscopic ultrasonography demonstrated a heterogeneous
tumor with small, cystic, hypoechoic spots originating from the second layer. The
patient was clinically asymptomatic, with no contributory family history or abnormal
laboratory data. The results of a physical examination, abdominal computed tomography,
and plain chest radiography were all unremarkable. Although the endoscopic tumor type
was determined to be SMT, the tumor was successfully resected by endoscopic submucosal
dissection (ESD) and subsequently diagnosed as a gastric hamartomatous inverted polyp
(GHIP). The findings of the present case highlight the importance of considering GHIP
as a diagnosis and indicate the utility of en bloc resection of GHIP with ESD.