An Update on Biomedical Application of Nanotechnology for Alzheimer’s Disease Diagnosis and Therapy

Y. Panahi; M. Mohammadhosseini; A. J. N. Abadi; A. Akbarzadeh; H. Mellatyar

doi:10.1055/s-0042-112811

Drug Research, Table of Contents

Drug Res (Stuttg) 2016; 66(11): 580-586
DOI: 10.1055/s-0042-112811

Review

An Update on Biomedical Application of Nanotechnology for Alzheimer’s Disease Diagnosis and Therapy

Y. Panahi

¹Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

,

M. Mohammadhosseini

⁵Department of Chemistry, Shahrood Branch, Islamic Azad University, Shahrood, Iran

,

A. J. N. Abadi

³Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

,

A. Akbarzadeh

⁶Stem Cell Research Center,Tabriz University of Medical Sciences, Tabriz, Iran

⁴Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran

,

H. Mellatyar

²Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran

⁴Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran

› Author Affiliations

Abstract

Approximately 35 million people worldwide suffer from Alzheimer’s disease (AD). The cellular uptake and specific transport of drugs and imaging agents to brain are common issues in the diagnosis and therapy of AD. New advances in nanotechnology have supplied favorable solutions to this issue. Various nanocarriers such as polymeric nanoparticles, liposomes, micelles, dendrimers and nanogels have been studied for the delivery of drugs and imaging agents to brain. This review presents a succinct discussion of the applications of nanotechnology for Alzheimer’s disease diagnosis and therapy.

Key words

Alzheimer’s disease - blood-brain barrier (BBB) - nanotechnology

Full Text

References

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