Drug Res (Stuttg) 2016; 66(11): 580-586
DOI: 10.1055/s-0042-112811
Review
© Georg Thieme Verlag KG Stuttgart · New York

An Update on Biomedical Application of Nanotechnology for Alzheimer’s Disease Diagnosis and Therapy

Y. Panahi
1   Chemical Injuries Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
,
M. Mohammadhosseini
5   Department of Chemistry, Shahrood Branch, Islamic Azad University, Shahrood, Iran
,
A. J. N. Abadi
3   Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
,
A. Akbarzadeh
6   Stem Cell Research Center,Tabriz University of Medical Sciences, Tabriz, Iran
4   Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
,
H. Mellatyar
2   Department of Medical Biotechnology, Faculty of Advanced Medical Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
4   Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran
› Author Affiliations
Further Information

Publication History

received 07 July 2016

accepted 12 July 2016

Publication Date:
04 October 2016 (online)

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Abstract

Approximately 35 million people worldwide suffer from Alzheimer’s disease (AD). The cellular uptake and specific transport of drugs and imaging agents to brain are common issues in the diagnosis and therapy of AD. New advances in nanotechnology have supplied favorable solutions to this issue. Various nanocarriers such as polymeric nanoparticles, liposomes, micelles, dendrimers and nanogels have been studied for the delivery of drugs and imaging agents to brain. This review presents a succinct discussion of the applications of nanotechnology for Alzheimer’s disease diagnosis and therapy.