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DOI: 10.1055/s-0042-117218
Semi-solid feeds may reduce the risk of aspiration pneumonia and shorten postoperative length of stay after percutaneous endoscopic gastrostomy (PEG)
Publication History
submitted
05 May 2016
accepted
after revision
20 August 2016
Publication Date:
15 November 2016 (online)

Background and study aims: Feeding-related adverse events after percutaneous endoscopic gastrostomy (PEG) such as aspiration pneumonia may result in prolonged hospitalization and postoperative mortality. This study evaluated the efficacy of using semi-solid feeds to reduce feeding-related adverse events and improve clinical outcomes.
Patients and methods: Patients who received PEG for enteral nutrition at our hospital between January 2014 and December 2015 were allocated to a postoperative feeding protocol that used either liquid feed or semi-solid feed. Baseline characteristics, postoperative feeding-related adverse events and clinical outcomes in the 2 groups were prospectively analysed and compared.
Results: One hundred and seventeen PEG patients (age range: 59 – 97 years, male: 53) were enrolled with 72 patients given liquid feed and 45 patients receiving semi-solid feed. Baseline characteristics were similar in both groups. The semi-solid feed group experienced fewer incidence of feeding-related aspiration pneumonia (2.2 % vs. 22.2 %, P < 0.005) and shorter postoperative hospital length of stay (12.7 days vs. 18.8 days, P < 0.01). Significant differences were not observed in the frequency of peristomal infection (11.1 % vs. 12.5 %, P = 0.82), feeding-related diarrhea (2.2 % vs. 12.5 %, P = 0.09) and 30-day mortality rates (2.2 % vs. 8.3 %, P = 0.25).
Conclusions: Semi-solid feeding may reduce the risk of aspiration pneumonia and shorten postoperative hospital length of stay after PEG. Semi-solid feeds are safe to use and can be employed either as a first line feeding protocol or an alternative when liquid feeding is unsuccessful.
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References
- 1 Gauderer MW, Ponsky JL, Izant Jr RJ. Gastrostomy without laparotomy: a percutaneous endoscopic technique. J Pediatr Surg 1980; 15: 872-875
- 2 DeLegge MH. Percutaneous endoscopic gastrostomy. Am J Gastroenterol 2007; 102: 2620-2623
- 3 Suzuki Y, Tamez S, Murakami A et al. Survival of geriatric patients after percutaneous endoscopic gastrostomy in Japan. World J Gastroenterol 2010; 16: 5084-5091
- 4 Richter-Schrag HJ, Richter S, Ruthmann O et al. Risk factors and complications following percutaneous endoscopic gastrostomy: a case series of 1041 patients. Can J Gastroenterol 2011; 25: 201-206
- 5 Laskaratos FM, Walker M, Walker M et al. Predictive factors for early mortality after percutaneous endoscopic and radiologically-inserted gastrostomy. Dig Dis Sci 2013; 58: 3558-3565
- 6 Azzopardi N, Ellul P. Pneumonia and mortality after percutaneous endoscopic gastrostomy insertion. Turk J Gastroenterol 2013; 24: 109-116
- 7 Nishiwaki S, Araki H, Goto N et al. Clinical analysis of gastroesophageal reflux after PEG. Gastrointest Endosc 2006; 64: 890-896
- 8 Jung SH, Dong SH, Lee JY et al. Percutaneous Endoscopic Gastrostomy Prevents Gastroesophageal Reflux in Patients with Nasogastric Tube Feeding: A Prospective Study with 24-Hour pH Monitoring. Gut Liver 2011; 5: 288-292
- 9 Lee TH, Shiun YC. Changes in gastroesophageal reflux in patients with nasogastric tube followed by percutaneous endoscopic gastrostomy. J Formos Med Assoc 2011; 110: 115-119
- 10 Horiuchi A, Nakayama Y, Sakai R et al. Elemental diets may reduce the risk of aspiration pneumonia in bedridden gastrostomy-fed patients. Am J Gastroenterol 2013; 108: 804-810
- 11 Kanie J, Suzuki Y, Iguchi A et al. Prevention of gastroesophageal reflux using an application of half-solid nutrients in patients with percutaneous endoscopic gastrostomy feeding. J Am Geriatr Soc 2004; 52: 466-467
- 12 Kanie J, Suzuki Y, Akatsu H et al. Prevention of late complications by half-solid enteral nutrients in percutaneous endoscopic gastrostomy tube feeding. Gerontology 2004; 50: 417-419
- 13 Jain NK, Larson DE, Schroeder KW et al. Antibiotic prophylaxis for percutaneous endoscopic gastrostomy. A prospective, randomized, double-blind clinical trial. Ann Intern Med 1987; 107: 824-828
- 14 Whelan K, Judd PA, Taylor MA. Assessment of fecal output in patients receiving enteral tube feeding: validation of a novel chart. Eur J Clin Nutr 2004; 58: 1030-1037
- 15 Adams GF, Guest DP, Ciraulo DL et al. Maximizing tolerance of enteral nutrition in severely injured trauma patients: a comparison of enteral feedings by means of percutaneous endoscopic gastrostomy versus percutaneous endoscopic gastrojejunostomy. J Trauma 2000; 48: 459-464
- 16 Tanishima Y, Fujita T, Suzuki Y et al. Effects of half-solid nutrients on gastroesophageal reflux in beagle dogs with or without cardioplasty and intrathoracic cardiopexy. J Surg Res 2010; 161: 272-277
- 17 Nishiwaki S, Araki H, Shirakami Y et al. Inhibition of gastroesophageal reflux by semi-solid nutrients in patients with percutaneous endoscopic gastrostomy. JPEN J Parenter Enteral Nutr 2009; 33: 513-519
- 18 Shimizu A, Muramatsu H, Kura T et al. Incidence of gastroesophageal reflux associated with percutaneous endoscopic gastrostomy contrast agent viscosity: a randomized controlled crossover trial. Eur J Clin Nutr 2016; [Epub ahead of print]
- 19 Adachi K, Furuta K, Morita T et al. Half-solidification of nutrient does not decrease gastro-esophageal reflux events in patients fed via percutaneous endoscopic gastrostomy. Clin Nutr 2009; 28: 648-651
- 20 Shizuku T, Adachi K, Furuta K et al. Efficacy of half-solid nutrient for the elderly patients with percutaneous endoscopic gastrostomy. J Clin Biochem Nutr 2011; 48: 226-229
- 21 Okabe T, Terashima H, Sakamoto A. Determinants of liquid gastric emptying: comparisons between milk and isocalorically adjusted clear fluids. Br J Anaesth 2015; 114: 77-82