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Klin Monbl Augenheilkd 2017; 234(04): 584-587
DOI: 10.1055/s-0042-119564
DOI: 10.1055/s-0042-119564
Der interessante Fall
Leberʼs Hereditary Optic Neuropathy, Normal Tension Glaucoma, and Flammer Syndrome: Long Term Follow-up of a Patient
Lebersche hereditäre Optikusneuropathie, Normaldruckglaukom und Flammer-Syndrom – eine langzeitige Beobachtung eines PatientenFurther Information
Publication History
Publication Date:
31 January 2017 (online)
Background
In our clinic, we observed a patient with the risk constellation of a mitochondrial DNA mutation (G7444A-mutation) combined with Flammer syndrome (FS) [1], [2], [3], who developed a classical phenotype of a Leberʼs hereditary optic neuropathy (LHON) in one eye, subsequently chronic progressive normal tension glaucoma (NTG) in the other eye, and finally, optic nerve compartment syndrome (ONCS) [4] and a marked increase in the retinal venous pressure (RVP) [5] on both sides. This stimulated the discussion of whether these individual clinical and laboratory findings were an accidental concurrence, or whether they were dependent on each other.
Abbreviations
FS:
Flammer syndrome
LHON:
Leberʼs hereditary optic neuropathy
NTG:
normal tension glaucoma
ONCS:
optic nerve compartment syndrome
ONH:
optic nerve head
PVD:
primary vascular dysregulation
RVP:
retinal venous pressure
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References
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