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CC BY-NC-ND 4.0 · Asian J Neurosurg 2022; 17(02): 310-316
DOI: 10.1055/s-0042-1750384
Case Report

Intratumoral and Peritumoral Brain Abscess Concomitant with Glioblastoma: Report of Two Cases with Review of Literature

Salman Shaikh
1   Department of Neurosurgery, University Hospital Coventry and Warwickshire, Coventry, United Kingdom
,
Hassan Othman
1   Department of Neurosurgery, University Hospital Coventry and Warwickshire, Coventry, United Kingdom
,
Iqra Marriyam
1   Department of Neurosurgery, University Hospital Coventry and Warwickshire, Coventry, United Kingdom
,
Santhosh Nagaraju
2   Department of Pathology, University Hospital Birmingham, Birmingham, United Kingdom
,
Gorana Kovacevic
3   Department of Infectious Diseases, University Hospital Coventry and Warwickshire, Coventry, United Kingdom
,
Ronan Dardis
1   Department of Neurosurgery, University Hospital Coventry and Warwickshire, Coventry, United Kingdom
› Author Affiliations Funding None.
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Abstract

Intracranial abscess coexistent with a high grade glioma, without prior surgical intervention, is an unusual occurrence. This paper presents two such cases with Nocardia farcinica abscess surrounding the glioblastoma in an immunocompromised individual and Enterococcus faecium abscess within the glioblastoma in an immunocompetent patient. Adjuvant therapy was tapered as per each patient's clinical response. Till date, only eight cases of coexistent high-grade glioma and brain abscess have been reported in literature. This report stands distinct in highlighting the need to radiologically evaluate each foci of a multicentric cranial lesion on its own merit.

Keywords

abscess - glioblastoma - intracranial - intratumoral - Nocardia - peritumoral

Ethical Approval

This article does not contain any studies with human participants or animals performed by any of the authors.


Informed Consent

Informed consent was obtained from all individual participants included in the study.




Publication History

Article published online:
25 August 2022

© 2022. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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