CC BY 4.0 · SynOpen 2023; 07(02): 186-208
DOI: 10.1055/s-0042-1751452
review
Virtual Collection Click Chemistry and Drug Discovery

Recent Advancements in Triazole-based Click Chemistry in Cancer Drug Discovery and Development

Arun Kumar
a   Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, 173229, India
,
Ashok Kumar Yadav
b   University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh, 160014, India
,
Vivek Mishra
c   Amity Institute of Click Chemistry Research and Studies, Amity University, Noida, Uttar Pradesh, 201301, India
,
Deepak Kumar
a   Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh, 173229, India
› Author Affiliations
V.M. is thankful to SERB New Delhi for TARE Project (TARE/2022/000673) for support.


Abstract

Triazole-based compounds possess a broad range of activity and can be synthesized using click chemistry. Many new chemotherapeutic agents have been developed in recent years by exploiting click chemistry and these are covered in this review.



Publication History

Received: 28 January 2023

Accepted after revision: 30 March 2023

Article published online:
17 May 2023

© 2023. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by/4.0/)

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