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DOI: 10.1055/s-0042-1751526
Recent Advances in the Multicomponent Synthesis of Heterocycles Using 5-Aminotetrazole
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Abstract
The unique reactivity and beneficial features of the 5-aminotetrazole synthon (1H-tetrazol-5-amine) have made it a versatile and effective building block in the synthesis of heterocyclic compounds. In addition, several drugs containing this scaffold with a wide array of biological properties have been already introduced. Heterocyclic structures are the backbone of many biologically active and industrially important compounds. 5-Aminotetrazole is one of the favored synthons used in the preparation of heterocycle-bearing compounds, especially in multicomponent synthesis. This review highlights a comprehensive overview of the emerging applications of 5-aminotetrazole as a key component in the synthesis of heterocyclic frameworks through multicomponent reactions, reported between 2017 and July 2023.
1 Introduction
2 5-Aminotetrazole
3 Tetrazolopyrimidine Compounds
4 Spiro Compounds
5 Miscellaneous
6 Conclusion
Key words
1H-tetrazol-5-amine - 5-aminotetrazole - heterocycles - multicomponent reactions - synthesisPublikationsverlauf
Eingereicht: 24. August 2023
Angenommen nach Revision: 24. Oktober 2023
Artikel online veröffentlicht:
08. Januar 2024
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