Physical activity during video capsule endoscopy correlates with shorter bowel transit time

Peter P. Stanich; Joshua Peck; Christopher Murphy; Kyle M. Porter; Marty M. Meyer

doi:10.1055/s-0043-115385

Endoscopy International Open, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Endosc Int Open 2017; 05(09): E856-E860
DOI: 10.1055/s-0043-115385

Original article

Physical activity during video capsule endoscopy correlates with shorter bowel transit time

Peter P. Stanich

¹Section of Capsule Endoscopy, Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States

,

Joshua Peck

¹Section of Capsule Endoscopy, Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States

,

Christopher Murphy

¹Section of Capsule Endoscopy, Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States

,

Kyle M. Porter

²Center for Biostatistics, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States

,

Marty M. Meyer

¹Section of Capsule Endoscopy, Division of Gastroenterology, Hepatology and Nutrition, The Ohio State University Wexner Medical Center, Columbus, Ohio, United States

› Institutsangaben

Abstract

Background and study aim Video capsule endoscopy (VCE) is limited by reliance on bowel motility for propulsion, and lack of physical activity has been proposed as a cause of incomplete studies. Our aim was to prospectively investigate the association between physical activity and VCE bowel transit.

Patients and methods Ambulatory outpatients receiving VCE were eligible for the study. A pedometer was attached at the time of VCE ingestion and step count was recorded at the end of the procedure. VCE completion was assessed by logistic regression models, which included step count (500 steps as one unit). Total transit time was analyzed by Cox proportional hazards models. The hazard ratios (HR) with 95 % confidence interval (CI) indicated the “hazard” of completion, such that HRs > 1 indicated a reduced transit time.

Results A total of 100 patients were included. VCE was completed in 93 patients (93 %). The median step count was 2782 steps. Step count was not significantly associated with VCE completion (odds ratio 1.45, 95 %CI 0.84, 2.49). Pedometer step count was significantly associated with shorter total, gastric, and small-bowel transit times (HR 1.09, 95 %CI 1.03, 1.16; HR 1.05, 95 %CI 1.00, 1.11; HR 1.07, 95 %CI 1.01, 1.14, respectively). Higher body mass index (BMI) was significantly associated with VCE completion (HR 1.87, 95 %CI 1.18, 2.97) and shorter bowel transit times (HR 1.05, 95 %CI 1.02, 1.08).

Conclusions Increased physical activity during outpatient VCE was associated with shorter bowel transit times but not with study completion. In addition, BMI was a previously unreported clinical characteristic associated with VCE completion and should be included as a variable of interest in future studies.

Volltext

Referenzen

References
1 Gong F, Swain P, Mills T. Wireless endoscopy. Gastrointest Endosc 2000; 51: 725-729
2 Liao Z, Gao R, Xu C. et al. Indications and detection, completion, and retention rates of small-bowel capsule endoscopy: a systematic review. Gastrointest Endosc 2010; 71: 280-286
3 Westerhof J, Weersma RK, Koornstra JJ. Risk factors for incomplete small-bowel capsule endoscopy. Gastrointest Endosc 2009; 69: 74-80
4 Robinson CA, Jackson C, Condon D. et al. Impact of inpatient status and gender on small-bowel capsule endoscopy findings. Gastrointest Endosc 2011; 74: 1061-1066
5 Yazici C, Losurdo J, Brown MD. et al. Inpatient capsule endoscopy leads to frequent incomplete small bowel examinations. World J Gastroenterol 2012; 18: 5051-5057
6 Keeling WF, Martin BJ. Gastrointestinal transit during mild exercise. J Appl Physiol 1987; 63: 978-981
7 Dainese R, Serra J, Azpiroz F. et al. Effects of physical activity on intestinal gas transit and evacuation in healthy subjects. Am J Med 2004; 116: 536-539
8 Shibuya T, Mori H, Takeda T. et al. The relationship between physical activity level and completion rate of small bowel examination in patients undergoing capsule endoscopy. Intern Med 2012; 51: 997-1001
9 Tudor-Locke C, Williams JE, Reis JP. et al. Utility of pedometers for assessing physical activity: convergent validity. Sports Med 2002; 32: 795-808
10 Bassett Jr DR. Validity and reliability issues in objective monitoring of physical activity. Res Q Exerc Sport 2000; 71: S30-36
11 Schneider PL, Crouter SE, Lukajic O. et al. Accuracy and reliability of 10 pedometers for measuring steps over a 400-m walk. Med Sci Sports Exerc 2003; 35: 1779-1784
12 Schneider PL, Crouter S, Bassett DR. Pedometer measures of free-living physical activity: comparison of 13 models. Med Sci Sports Exerc 2004; 36: 331-335
13 Shim KN, Jeon SR, Jang HJ. et al. Quality indicators for small bowel capsule endoscopy. Clin Endosc 2017; 50: 148-160
14 Sadik R, Stotzer PO, Simren M. et al. Gastrointestinal transit abnormalities are frequently detected in patients with unexplained GI symptoms at a tertiary centre. Neurogastroenterol Motil 2008; 20: 197-205
15 Spada C, Riccioni ME, Urgesi R. et al. Capsule endoscopy in celiac disease. World J Gastroenterol 2008; 14: 4146-4151
16 Kleinman B, Stanich PP, Betkerur K. et al. Opioid use is not associated with incomplete wireless capsule endoscopy for inpatient or outpatient procedures. Diagn Ther Endosc 2014; 2014: 651259
17 Lee MM, Jacques A, Lam E. et al. Factors associated with incomplete small bowel capsule endoscopy studies. World J Gastroenterol 2010; 16: 5329-5333
18 Triantafyllou K, Kalantzis C, Papadopoulos AA. et al. Video-capsule endoscopy gastric and small bowel transit time and completeness of the examination in patients with diabetes mellitus. Dig Liver Dis 2007; 39: 575-580